The effect of splenectomy on the hematology and on the activity of δ-aminolevulinic acid dehydratase (ALA-D) in hemopoietic tissues of the dogfish, Scyliorhinus canicula (elasmobranchii)

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Abstract

  • 1.

    The effects of splenectomy on some hematological parameters and on the activity of ALA-D in some tissues of the dogfish, Scyliorhinus canicula, were studied.

  • 2.

    Splenectomy induced an immediate decrease in hematocrit which recovered after 3 weeks.

  • 3.

    Hemoglobin content and the mean corpuscle hemoglobin concentration did not change during the period.

  • 4.

    No difference in the total WBC count was observed. However, the relative abundance of spindle cells and blast cells decreased, while neutrophilic and eosinophilic granulocytes increased.

  • 5.

    In the blood the ALA-D activity decreased during the first 2 weeks, then it increased, reaching the control level after 3 weeks. There was a successive increase of ALA-D activity in the epigonal organ, the organ of Leydig and the kidney.

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