Second-generation Hybrid capture test and Amplicor monitor test generate highly correlated hepatitis B virus DNA levels

doi:10.1016/S0166-0934(01)00359-7

Journal of Virological Methods

Volume 97, Issues 1–2, September 2001, Pages 165-169

https://doi.org/10.1016/S0166-0934(01)00359-7 Get rights and content

Abstract

The performance of the Digene Hybrid Capture II HBV DNA Test HC II and the Roche Cobas Amplicor Monitor Test (Cobas-HBV) was evaluated on 252 serum samples. One hundred and seventy-three samples were HBV DNA positive and 75 HBV DNA negative by both assays. Four samples were HBV DNA positive by Cobas-HBV only. Linear regression analysis showed that the HBV DNA concentrations obtained from both assays were significantly related (n=173, r=0.976, P<0.0001). The results of the study show that Hybrid capture II and Cobas-HBV could be used equally in the management for patients with chronic HBV infection.

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Brief reportSecond-generation Hybrid capture test and Amplicor monitor test generate highly correlated hepatitis B virus DNA levels

Abstract

J. Virol. Methods

J. Virol. Methods

J. Virol. Methods

J. Virol. Methods

Quantitative detection of hepatitis B virus DNA in two international reference plasma preparations

J. Clin. Microbiol.

Comparison of the second-generation Digene Hybrid-Capture assay with the branched-DNA assay for measurement of hepatitis B virus DNA in serum

J. Clin. Microbiol.

Laboratory diagnosis of viral hepatitis

Identification of different states of hepatitis B virus infection with a quantitative PCR assay

Clin. Diagn. Lab. Immunol.

Brief report
Second-generation Hybrid capture test and Amplicor monitor test generate highly correlated hepatitis B virus DNA levels