A Pilot Randomized Controlled Study on the Effect of Laser Photocoagulation of Confluent Soft Macular Drusen
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2023, Biomedicine and PharmacotherapyDrusen regression is associated with local changes in fundus autofluorescence in intermediate age-related macular degeneration
2013, American Journal of OphthalmologyLaser Treatment in Patients with Bilateral Large Drusen. The Complications of Age-Related Macular Degeneration Prevention Trial
2006, OphthalmologyCitation Excerpt :Previous studies had provided important information that influenced the CAPT study design and treatment protocol. These included the following: (1) fellow eyes of participants with unilateral late AMD have an increased risk of developing choroidal neovascularization after prophylactic laser treatment; (2) laser treatment delivered in a grid or scatter pattern typically did not cause persistent or symptomatic scotomata; (3) laser burns could be applied either directly to drusen or adjacent to drusen with no discernible long-term difference in terms of promoting resolution of drusen or causing side effects; (4) more intense laser burns were associated with a tendency to develop choroidal neovascularization, sometimes at the site of the laser burn; and (5) laser application could be repeated after an interval of 6 to 12 months to promote further resolution of drusen without any apparent significant adverse effect.8,9,12,13,15,16,44 Laser treatment in the CAPT had no effect at 5 years on either VA or the incidence of late AMD (Figs 4, 5).
Long-Term Effect of Laser Treatment for Dry Age-Related Macular Degeneration on Choroidal Hemodynamics
2006, American Journal of OphthalmologyCitation Excerpt :This increase in flow is mainly the result of an increase in blood volume; this may be attributable to vasodilatation. Many studies have shown evidence suggesting that laser photocoagulation treatment can reduce the number of drusen in patients with AMD.6–8,11–13 Although the exact mechanism by which laser treatment causes drusen resolution is not known, it is possible that the choroidal circulation may play a role in this phenomenon.
Age-Related Macular Degeneration: Nonneovascular Early AMD, Intermediate AMD, and Geographic Atrophy
2005, Retina: Fourth Edition
Presented at the American Academy of Ophthalmology Annual Meeting, Atlanta, November 1995. The authors have no proprietary interest in any of the materials used in this study.