Original articleAntibiotic resistance patterns of ocular bacterial flora: A prospective study of patients undergoing anterior segment surgery☆
Section snippets
Patients and methods
All patients scheduled for anterior segment intraocular surgery at Stanford University were asked to participate in this prospective study. After obtaining approval from the Institutional Review Board at Stanford University, consecutive patients who gave consent participated in the study. A total of 156 eyes from 139 patients were enrolled in the study from August 2001 to February 2002. Patients receiving topical ophthalmic medications or systemic antibiotics were not excluded from the study,
Results
Among the 156 patients participating in the study, 17 had surgery in both eyes. To avoid paired bias, only the first operated eye of each patient was included in the data analysis. Furthermore, 19 patients had more than one surgery in the same eye, and, therefore, only the first surgery was included in the study, yielding 120 eyes from 120 patients. The mean and median ages of study participants were 69.3 and 73.0 years, respectively. There were 53 male and 67 female patients. Of the 120 eyes,
Discussion
One of the goals of postoperative endophthalmitis prophylaxis is to reduce the number of eyelid and conjunctival bacteria that are present at the time of surgery. It has been shown that preoperative application of both topical povidone-iodine and various antibiotic agents is effective in reducing the incidence of ocular contamination as measured by the growth of bacterial colonies in conjunctival isolates.2, 3, 4, 12, 13, 14, 15, 16, 17 Most cataract surgeons in the United States place their
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Manuscript no. 220611.
Supported by the Edward E. Hills Foundation, San Francisco, California, and Hannelore-Georg Zimmerman Foundation, Munich, Germany.
The authors have no proprietary interest in any of the products used in this study.