Letters to the EditorLUPUS ANTICOAGULANT: A FAMILIAL OBSERVATION
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Cited by (24)
Antiphospholipid syndrome's genetic and epigenetic aspects
2019, Autoimmunity ReviewsCitation Excerpt :They found the paternal haplotype A30; Cw3; B60; DR4; DRw53; DQw3 to be associated with aCL. The occurrence of LA in families carrying haplotypes that contained either DR4 or DR7 also has been reported by others [13,14]. May et al. have described a family, including identical twins and their mother, in which all members had SLE and presented with different manifestations of APS [15].
Genetic and Epigenetic Aspects of Antiphospholipid Syndrome: What we knew, what we know
2017, Handbook of Systemic Autoimmune DiseasesGenetic aspects of the antiphospholipid syndrome: An update
2016, Autoimmunity ReviewsCitation Excerpt :They found the paternal haplotype A30; Cw3; B60; DR4; DRw53; DQw3 to be associated with aCL. The occurrence of LA in families carrying haplotypes that contained either DR4 or DR7 also has been reported by others [10,11]. May et al. have described a family, including identical twins and their mother, in which all members had SLE and presented with different manifestations of APS [12].
Chapter 6 Genetic Aspects of the Antiphospholipid Syndrome: HLA Associations
2009, Handbook of Systemic Autoimmune DiseasesCitation Excerpt :They found the paternal haplotype A30; Cw3; B60; DR4; DRw53; DQw3 to be associated with aCL. The occurrence of LAC in families carrying haplotypes that contained either DR4 or DR7 also has been reported by others (Rouget et al., 1982; Mackie et al., 1987). May et al., have described a family, including identical twins and their mother, in which all members had SLE and presented with different manifestations of APS (May et al., 1993).
Histocompatibility Class I and II Antigens in Extensive Kindred With Sneddon's Syndrome and Related Hypercoagulation Disorders
2007, Human ImmunologyCitation Excerpt :Studies on systemic lupus erythematosus regarding aCL and the histocompatibility class I and II antigens reported association with DR7 in Italian patients [4] and with DR4 in patients from the United Kingdom [5]. DR4 and DR7 antigens have also been reported to be associated with familial LA in systemic lupus erythematosus [6–8]. Moreover, association between primary antiphospholipid syndrome (PAPS) and the histocompatibility class I and II antigen DR4 has been present in patients from the United Kingdom, with systemic lupus erythematosus [9]; in a series of 13 patients with PAPS from this very region, Asherson et al. [10] found that HLA-DR4 was present in 10 patients and DRw53 was present in 12 patients, suggesting that a higher relative risk for PAPS was conferred by the DRw53 allele, which was present in all aCL-positive patients.
HLA class II alleles and genetic predisposition to the antiphospholipid syndrome
2003, Autoimmunity Reviews