Elsevier

The Lancet

Volume 320, Issue 8289, 10 July 1982, Page 105
The Lancet

Letters to the Editor
LUPUS ANTICOAGULANT: A FAMILIAL OBSERVATION

https://doi.org/10.1016/S0140-6736(82)91726-3Get rights and content

References (6)

There are more references available in the full text version of this article.

Cited by (24)

  • Antiphospholipid syndrome's genetic and epigenetic aspects

    2019, Autoimmunity Reviews
    Citation Excerpt :

    They found the paternal haplotype A30; Cw3; B60; DR4; DRw53; DQw3 to be associated with aCL. The occurrence of LA in families carrying haplotypes that contained either DR4 or DR7 also has been reported by others [13,14]. May et al. have described a family, including identical twins and their mother, in which all members had SLE and presented with different manifestations of APS [15].

  • Genetic aspects of the antiphospholipid syndrome: An update

    2016, Autoimmunity Reviews
    Citation Excerpt :

    They found the paternal haplotype A30; Cw3; B60; DR4; DRw53; DQw3 to be associated with aCL. The occurrence of LA in families carrying haplotypes that contained either DR4 or DR7 also has been reported by others [10,11]. May et al. have described a family, including identical twins and their mother, in which all members had SLE and presented with different manifestations of APS [12].

  • Chapter 6 Genetic Aspects of the Antiphospholipid Syndrome: HLA Associations

    2009, Handbook of Systemic Autoimmune Diseases
    Citation Excerpt :

    They found the paternal haplotype A30; Cw3; B60; DR4; DRw53; DQw3 to be associated with aCL. The occurrence of LAC in families carrying haplotypes that contained either DR4 or DR7 also has been reported by others (Rouget et al., 1982; Mackie et al., 1987). May et al., have described a family, including identical twins and their mother, in which all members had SLE and presented with different manifestations of APS (May et al., 1993).

  • Histocompatibility Class I and II Antigens in Extensive Kindred With Sneddon's Syndrome and Related Hypercoagulation Disorders

    2007, Human Immunology
    Citation Excerpt :

    Studies on systemic lupus erythematosus regarding aCL and the histocompatibility class I and II antigens reported association with DR7 in Italian patients [4] and with DR4 in patients from the United Kingdom [5]. DR4 and DR7 antigens have also been reported to be associated with familial LA in systemic lupus erythematosus [6–8]. Moreover, association between primary antiphospholipid syndrome (PAPS) and the histocompatibility class I and II antigen DR4 has been present in patients from the United Kingdom, with systemic lupus erythematosus [9]; in a series of 13 patients with PAPS from this very region, Asherson et al. [10] found that HLA-DR4 was present in 10 patients and DRw53 was present in 12 patients, suggesting that a higher relative risk for PAPS was conferred by the DRw53 allele, which was present in all aCL-positive patients.

View all citing articles on Scopus
View full text