Fe(II)-mediated fragmentation of 1,4-diaryl-2,3-dioxabicyclo[2.2.2]octanes through competitive single electron transfer pathway and Lewis acid pathway
Reactions of 1 with FeBr2 afforded various fragmentation products. The fragmentation mechanism was proposed and the antimalarial activities of 1 were tested.
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Acknowledgements
We are grateful to Professor Eietsu Hasegawa (Faculty of Science, Niigata University), Professor Tsutomu Miyashi and Dr. Hiroshi Ikeda (Faculty of Science, Tohoku University), Professor Yasutake Takahashi (Faculty of Engineering, Mie University), and Professor Akinori Kon-no (Faculty of Engineering, Shizuoka University) for their helpful comments and assistance.
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