X=Y-ZH systems as potential 1,3-dipoles. Part 48. Enantiopure cycloadducts from oxime-nitrone-isoxazolidine cascades☆
Enantiopure cycloadducts have been prepared in good yield via oxime-nitrone-isoxazolidine cascade reactions involving the nucleophilic opening of enantiopure epoxides with oximes followed by 1,3-dipolar cycloaddition reactions with suitable dipolarophiles.
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Part 47. Markandu, J.; Dondas, H.A.; Frederickson, M.; Grigg, R. Tetrahedron, 1997, 53, in press.
Copyright © 1997 Published by Elsevier Ltd.