Original articleReduced basal ganglia volumes in trichotillomania measured via morphometric magnetic resonance imaging
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2018, NeuroImage: ClinicalCitation Excerpt :Structural imaging studies comparing patients with trichotillomania to controls have yielded mixed results with regards to the basal ganglia. One study found no volumetric changes in the caudate (Stein et al., 1997), one found no difference in the global basal ganglia (Roos et al., 2015), one found reduced left putamen volumes (O'Sullivan et al., 1997), and another found excess grey matter density in left putamen and amygdala (Chamberlain et al., 2008). Due to the relatively limited research scrutiny of this disorder, and limited funding, imaging studies have typically involved relatively small sample sizes.
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This project was funded in part by the David Judah Research Fund. Dr. O'Sullivan was supported in part by a NIMH National Research Service Award for Clinical Research in Biological and Social Psychiatry (NIMH T32MH16259). Dr. Rauch was supported in part by the Pfizer-sponsored Harvard-MIT Clinician Investigator Training Program and grant MH01215 from the NIMH.