Effect of multivalent cations on the adhesion rate of cellular surfaces bearing ionizable groups☆

https://doi.org/10.1016/0927-7757(94)03050-AGet rights and content

Abstract

The effect of the presence of multivalent cations in a suspension medium on the rate of adhesion of a charge-regulated cell is investigated theoretically. By using sheep leucocytes as an illustrative example, it is found that the presence of multivalent cations has the effect of decreasing the rate of adhesion of the cells. On the basis of the concept of the Donnan potential, it is found that the magnitude of the electrostatic force for an ion-penetrable membrane is much smaller than that for an ion-impenetrable cell membrane. Under a fixed concentration of cations in the suspension medium, the rate of adhesion of the cells increases with the Péclet number, aspect ratio and Hamaker constant.

References (26)

  • Y.I Chang

    Colloids Surfaces

    (1989)
  • Y.I Chang

    J. Theor. Biol.

    (1989)
  • H Ohshima et al.

    Biophys. J.

    (1985)
  • H Ohshima et al.

    J. Theor. Biol.

    (1987)
  • B.W Ninham et al.

    J. Theor. Biol.

    (1971)
  • S Levine et al.

    Biophys. J.

    (1983)
  • H Brenner

    Chem. Eng. Sci.

    (1961)
  • S.L Goren et al.

    Chem. Eng. Sci.

    (1971)
  • A.J Goldman et al.

    Chem. Eng. Sci.

    (1967)
  • J Gregory

    J. Colloid Interface Sci.

    (1981)
  • D.C Prieve et al.

    J. Theor. Biol.

    (1976)
  • D.J Wilkins et al.

    J. Theor. Biol.

    (1962)
  • R Rajagopalan et al.

    J. Colloid Interface Sci.

    (1981)

    • Cited by (3)

    • The electrostatic behavior of the bacterial cell wall using a smoothing function to describe the charge-regulated volume charge density profile

      2015, Colloids and Surfaces B: Biointerfaces
      Citation Excerpt :

      According to the general notion, cations display a less important specific ion effect on biological surfaces than anions. Many studies have shown that the binding constants of monovalent ions onto biological surfaces are negligible [44–46]. Although we have not considered the specific cation effect, it is important to highlight that Medda et al. [47] have investigated the cation specific effects on the aggregation of hemoglobin at low and physiological salt concentration in the pH range 4.5–9.5.

    • The initial common pathway of inflammation, disease, and sudden death

      2012, Entropy

    • Effects of monoclonal antibodies, cationized ferritin, and other organic molecules on adhesion of Pasteuria penetrans endospores to Meloidogyne incognita

      1997, Journal of Nematology
    ☆

    Presented at the International Symposium on Electrokinetic Phenomena '93, held in Granada, Spain, 13–16 September 1993.

    View full text
    Copyright © 1995 Published by Elsevier B.V.