Post-mortem toxico-kinetics of trazodone
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Cited by (35)
Postmortem distribution of trazodone concentrations
2015, Forensic Science InternationalCitation Excerpt :Postmortem concentrations, on the other hand, have been described after an overdose with 2–4 g trazodone at a blood concentration of 15 mg/L, and liver 57 mg/kg [13]. Two other cases were found to have concentrations of 14.4 and 15.5 mg/L in blood, and 73.7 and 82.4 mg/kg in liver [14]. Three subjects with blood concentrations of 9.0, 24.3 and 32.9 mg/L were determined as deaths attributed primarily to trazodone [15].
Evaluation of postmortem redistribution phenomena for commonly encountered drugs
2012, Forensic Science InternationalCitation Excerpt :For remaining drugs, the interpretation of PMR was not performed because of statistical limitation (n = 1). Studies on amitriptyline [4,18,28,31,33,34,54,55], carbamazepine [28,30,31,36,37], tramadol [22,46,56–59] and trazodone [47–49,60–63] related deaths and PMR have frequently been reported. Propofol related deaths [64–69] have frequently been reported, but studies on PMR of propofol have not been reported.
Fatal blood and tissue concentrations of more than 200 drugs
2004, Forensic Science InternationalA target concentration strategy to determine ibuprofen dosing in children
2019, Paediatric Anaesthesia