Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in gabaergic neurons: Vesicular versus non-vesicular release of GABA
References (91)
- et al.
High- and low-affinity GABA-receptors in cultured granule cells regulate transmitter release by different mechanisms
Neurochem. Int.
(1991) - et al.
Calcium-independent GABA release from striatal slices the role of calcium channels
Neuroscience
(1990) - et al.
Characterization of the receptor-mediated sulphur ammo acid-evoked release of [3H]d-aspartate from primary cultures of cerebellar granule cells
Neurochem. Int.
(1990) - et al.
Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons
Int. J. devl Neurosci.
(1991) - et al.
Effects of valproate, vigabatrin and aminooxyacetic acid on release of endogenous and exogenous GABA from cultured neurons
Epilepsy Res.
(1988) - et al.
GABA influences the ultrastructure composition of cerebellar granule cells during development in culture
Int. J. devl Neurosci.
(1984) - et al.
Nervous tissue culture—a model to study action and uptake of putative neurotransmitters such as amino acids
Brain Res.
(1973) Bioenergetics of neurotransmitter transport
Biochim. biophys. Acta
(1983)- et al.
Photochemically generated cytosolic calcium pulses and their detection by fluo-3
J. biol. Chem.
(1989) - et al.
Characterization of the uptake of GABA, nipecotic acid and cis-4-OH-nipecotic acid in cultured neurons and astrocytes
Neurochem. Int.
(1985)
GABA uptake inhibitors: Kinetics and molecular pharmacology
Adv. Biosci.
Inhibition of K+-evoked [3H]D-aspartate release and neuronal calcium influx by verapamil, diltiazem and dextromethorphan: evidence for non-L/non-N voltage-sensitive calcium channels
Eur. J. Pharmac.
Amino acid neurotransmission: spotlight on synaptic vesicles
Trends Neurosci.
Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores
J. biol. Chem.
Effects of manganese and cobalt on the inhibitory synapse of the crustacean strech receptor neurons
Brain Res.
A23187: a divalent cation ionophore
J. biol. Chem.
Immunoelectron microscopic localization of synaptophysin in a Golgi subcompartment of developing hypothalamic neurons
Neuroscience
Multiple types of neuronal calcium channels and their selective modulation
Trends Neurosci.
Development of binding sites for excitatory amino acids in cultured cerebral cortex neurons
Int. J. devl Neurosci.
Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists
Trends pharmac. Sci.
Preparation of cell bodies from the developing cerebellum: structural and metabolic integrity of the isolated cells
Brain Res.
Macromolecular sites for specific neuroioxins and drugs on chemosensitive synapses and electrical excitation in biological membranes
Ion Channels
Orally active and potent inhibitors of γ-aminobutyric acid uptake
J. med. Chem.
Toward a molecular understanding of synaptic transmitter release: Physiological clues from the squid giant synapse
Role for iontropic and metabotropic receptors in quisqualate-stimulated inositol polyphosphate accumulation in rat cerebral cortex
Molec. Pharmac.
Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells
J. Neurochem.
3H-d-Aspartate release from cerebellargranule neurons is differentially regulated by glutamate, and K+-stimulation
J. Neurosci. Res.
Calcium-independent release of amino acid neurotransmitters: fact or artifact?
Prog. Neurobiol.
Glutamate mediates a slow synaptic response in hippocampal slice cultures
Calcium and transmitter release
Int. Rev. Neurobiol.
2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation
Neurosci. Lett.
On the site of origin of transmitter amino acids released by depolarization of nerve terminals in vitro
J. Neurochem.
The effects of methyl (2-thienyl-carbonyl)H-benzimidazolyl-2-carbamate, a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro
Cancer Res.
Cooperative action of calcium ions in transmitter release at the neuromuscular junction
J. Physiol.
Excitatory amino acid-induced release of3H-GABA from cultured mouse cerebral cortex interneurons
J. Neurosci.
Stimulation of γ-[3H]-aminobutyric acid release from cultured mouse cerebral cortex neurons by sulphur-containing excitatory amino acid transmitter candidates: receptor activation mediates two distinct mechanisms of release
J. Neurochem.
Glutamate: a neurotransmitter in mammalian brain
J. Neurochem.
Dantrolene prevents glutamate cytotoxicity and Ca2+ release from intracellular stores in cultured cerebral cortical neurons
J. Neurochem.
Mobilization of dantrolene sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-d-aspartate but not by 2-ammo-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate) and kainate in cultured cerebral cortical neurons
Uptake of γ-aminobutyric acid by a synaptic vesicle fraction isolated from rat brain
J. Neurochem.
Comparison of the properties of gamma-aminobutyric acid andl-glutamate uptake into synaptic vesicles isolated from rat brain
J. Neurochem.
Expression of excitatory amino acid receptors by cerebellar cells of the type-2 astrocyte cell lineage
J. Neurochem.
GABA release triggered by the activation of neuron-Uke non-NMDA receptors in cultured type-2 astrocytes is carrier-mediated
Glia
Calcium antagonism and calcium entry blockade
Pharmac. Rev.
Glutamate receptor structure function
Cited by (128)
Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction
2019, Current Topics in MembranesCitation Excerpt :Especially, stimulation of extrasynaptic iGluRs is deleterious by causing aberrant entry of Na+ and membrane depolarization (Tymianski, 2011). On the other hand, glutamate is well known to induce release of gamma-aminobutyric acid (GABA) from GABAergic neurons (Belhage, Hansen, & Schousboe, 1993; Erdo, Cai, & Lakics, 1993; Harris & Miller, 1989; Pin & Bockaert, 1989; Weiss, 1988). GABA release was also observed upon ischemia in hippocampal slices containing not only neurons but also numerous astrocytes (Inglefield & Schwartz-Bloom, 1998).
Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons
2017, Neurochemistry InternationalCitation Excerpt :However, primary cultures obtained using this protocol, contain a small (10%) metabolically active population of astrocytes (Drejer et al., 1985). Cells were cultured for 7–8 days at which time the cultures from cerebral neocortex consist of ∼70% highly differentiated GABAergic neurons (Belhage et al., 1993; Drejer et al., 1987) while the cultures from cerebellum consist of ∼90% glutamatergic neurons (Drejer and Schousboe, 1989). Therefore, these cultures constitute a valid experimental model system to study GABAergic and glutamatergic neurons.
Advances in understanding the functions of native GlyT1 and GlyT2 neuronal glycine transporters
2016, Neurochemistry International
- †
Present address: Colorado State University, Department of Anatomy and Neurobiology, Anatomy Building, Fort Collings, CO 80523, U.S.A.