Sterol composition of three marine sponge species from the genus Cinachyrella

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Abstract

  • 1.

    1. The hitherto undescribed sterol compositions of three marine sponge species belonging to the genus Cinachyrella are reported: C. alloclada and C. kükenthali from the Senegalese coast, at two different depths, and C. aff. schulzei from the lagoon of Nouméa, New Caledonia.

  • 2.

    2. Fourteen free sterols have been identified by GC and GC/MS studies, including the 23,24ξ-dimethylcholesta-5,22-dien-3β-ol (10) and the rare 24-norcholesta-5,22-dien-3β-ol (1).

  • 3.

    3. The first compound (10) is reported for the second time in a marine sponge and it was found only in Senegalese sponges collected in shallow waters.

  • 4.

    4. Sterol (10) has been isolated by HPLC and identified by NMR techniques.

  • 5.

    5. Significant amounts of cholest-7-en-3β-ol (7) were also found in the Senegalese sponge species.

  • 6.

    6. Apart from these two compounds, the three sponge sterol compositions are found to be very similar.

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