Elsevier

Neuroscience Letters

Volume 162, Issues 1–2, 12 November 1993, Pages 9-11
Neuroscience Letters

Properties of the mouse cone-mediated electroretinogram during light adaptation

https://doi.org/10.1016/0304-3940(93)90547-XGet rights and content

Abstract

Cone-mediated electroretinograms (ERGs) were obtained from normal mice during the course of light adaptation to a rod-desensitizing adapting field. Responses obtained during the early minutes of light adaptation were smaller in amplitude, and delayed in implicit time in comparison to responses obtained to the same stimulus presented later during light adaptation. These changes resemble those observed in the human cone ERG obtained under similar stimulus conditions, and indicate that the underlying mechanism may be similar. While the use of an adapting field appears to isolate the mouse cone ERG, these adaptation-induced changes should be considered when evaluating this response.

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