Apoptosis: A programmed cell death involved in ovarian and uterine physiology

doi:10.1016/0301-2115(96)02467-0

European Journal of Obstetrics & Gynecology and Reproductive Biology

Volume 67, Issue 2, August 1996, Pages 85-102

https://doi.org/10.1016/0301-2115(96)02467-0 Get rights and content

Abstract

Apoptosis is a form of programmed cell death which occurs through the activation of a cell-intrinsic suicide machinery. The biochemical machinery responsible for apoptosis is expressed in most, if not all, cells. Contrary to necrosis, an accidental form of cell death, apoptosis does not induce inflammatory reaction noxious for the vicinity. Apoptosis is primarily a physiologic process necessary to remove individual cells that are no longer needed or that function abnormally. Apoptosis plays a major role during development, homeostasis. Many stimuli can trigger apoptotic cell death, but expression of genes can modulate the sensibility of the cell. The aim of this review is to summarise current knowledge of the molecular mechanisms of apoptosis and its roles in human endometrium and ovary physiology.

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Review articleApoptosis: A programmed cell death involved in ovarian and uterine physiology

Abstract

Int Rev Exp Pathol

J Biol Chem

FEBS Lett

Trend Cell Biol

Biochem Pharm

J Biol Chem

J Biol Chem

J Biol Chem

J Biol Chem

Curr Opin Cell Biol

Cell Calcium

Exp Cell Res

FEBS Lett

Cell

J Biol Chem

Cell

Cell

Immunol Today

Eur J Canc

Exp Cell Res

Brain Res

Brain Res Cogn Brain Res

Brain Dev

Curr Opin Immunol

J Hepatol

Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview

Cancer Metast Rev

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics

Br J Cancer

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

Nature

Apoptosis: the biochemistry and molecular biology of programmed cell death

Endocrine Rev

Adrenocortical cell deletion: the role of ACTH

J Pathol

Endogenous endonuclease induced DNA fragmentation: an early event in cell-mediated cytolysis

Activation of programmed cell death in the rat ventral prostate after castration

Endocrinology

Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells

J Immunol

Biochemical evidence for programmed cell death in rabbit uterine epithelium

Am J Pathol

Transforming growth factor β1 induces apoptotic cell death in cultured human gastric carcinoma cells

Cancer Res

Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation

Biochem J

Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis

Int J Radiat Biol

genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T Lymphocytes

Mol Cell Biol

Glucocorticoid activation of a calciumdependant endonuclease in thymocyte nuclei leads to cell death

J Immunol

A new function for an old enzyme: the role of DNase I in apoptosis

Curr Top Microbiol Immunol

Characterization of the endognenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis programmed cell death

EMBO J

Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes

J Exp Med

Stimulation of endogenous endonuclease in cells exposed to oxydative stress

Toxicol Lett

Calcium dependance of glucocorticoid induced lymphocytolysis

Calcium-dependant cell death

Role of the endonuclease, protein kinase C, and chromatin conformation

Ann NY Acad Sci

Role of calcium in the programmed cell death of rat ventral prostatic glandular cells

Prostate

Increased activity of L-type Ca2+ channels exposed to serum from patients with type 1 diabetes

Science

Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin

J Biol Chem

Dexamethasoneinduced killing of neoplastic cells of lymphoid derivation: lack of early calcium involvement

J Cell Physiol

Elevation in cytosolic free Ca2+ are not required to trigger apoptosis in human leukemia cells

Clin Exp Immunol

Review article
Apoptosis: A programmed cell death involved in ovarian and uterine physiology