A medical evaluation of the use of qat in North Yemen

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Abstract

The data presented in this paper examine the frequent statements that the regular use of the drug qat by the people of North Yemen is harmful to their health. The research strategy employed performance of blind physical examinations as well as extensive interviews with 335 females and 371 males in and around the cities of Sanaa, Taiz and Hodeida who had been selected using a quota sample. The sample was classified into heavy, light and non-chewers of the qat plant, and systematic comparisons were made. In general, few diseases or conditions occurred with enough frequency to permit detailed analysis and fewer yet were associated with qat-use. Where associations occurred, differences by sex were often strong. Conditions most strongly associated with use by both sexes were histories of gastritis and insomnia, and the general body system groupings of gastrointestinal disorders. In males the strongest associations were with the histories of anorexia, constipation, insomnia and headaches, as well as the general history of respiratory difficulties. In females strong associations were seen between qat-use and the diagnosis of acute gastritis, and histories of jaundice, bronchitis and hepatic diseases. When effects of age and residence were corrected for by Mantel-Haenszel odds ratios on these items, some of the associations were diminished even further. In general, remarkably few of the allegations regarding the direct effects of qat-use on health by Western visitors to Yemen were supported by this study.

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This research was primarily made possible by DHEW Grant 5 R01 00974-03, under the auspices of the National Institute of Drug Abuse (NIDA). Supplementary support for a prelimineary survey and for later analysis was provided by the Neuropsychiatric Institute of U.C.L.A.

For the present paper J. G. Kennedy had primary responsibility for the project as a whole, for collecting the data in Yemen, and for drafting the article. James Teague had responsibility for design of the medical aspects of the project, participated in the field research, and shared in the analysis. William Rokaw was primarily responsible for the statistical analysis and participated in the final write-up. Elizabeth Cooney assisted with computer analysis, and library research. We thank Wendy Utsuki for her careful reading of the manuscript and Vicki Stringer for her patience in typing many drafts.

In Yemen Fathy Salem Ali al Beidnay, Mohammed Al Shamy and Abdo Ali Othman each served as field director for a phase of the overall data collecting process. Judith Obermeyer, Martha Mundy, Ahmad Makky and Kalthum Ali each directed regional surveys. Thanks are also extended to the eleven physicians who did the examinations and to Muhammad Abdul Wahid, Ahmad Marwani and Qadi Ismail al Akwa for their generous assistance. Many other Yemenis participated and we are thankful for their help, even though space here does not permit a complete listing.

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