Continuous ambulatory peritoneal dialysis-associated peritonitis as a model device-related infection: phenotypic adaptation, the staphylococcal cell envelope and infection
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2013, Research in MicrobiologyCitation Excerpt :Staphylococcus aureus is an important human pathogen that causes a wide spectrum of diseases ranging from benign skin infections to life-threatening endocarditis and toxic shock syndrome. The staphylococcal cell envelope is of fundamental importance for growth and cell division, interaction with the environment, pathogenesis, antibiotic resistance and immune evasion (Gatlin et al., 2006; Grundling and Schneewind, 2006; Williams et al., 1995). Autolysis, which plays an essential role in cell wall turnover, can be triggered by antibiotics or adverse physiological conditions (Brunskill and Bayles, 1996; Ramadurai and Jayaswal, 1997).
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