Original paperSingle-dose radiotherapy (6 Gy): palliation in painful bone metastases
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Cited by (56)
Re-irradiation for painful bone metastases - A systematic review
2014, Radiotherapy and OncologyCitation Excerpt :Jeremic et al. found pathological fractures to occur in 2.2% of patients after retreatment [14]. The remaining studies did not report any pathological fractures [1,4,9–13,15–21]. Mithal et al. found that patients who previously had a complete response were more likely to achieve pain response upon retreatment.
Effectiveness of reirradiation for painful bone metastases: A systematic review and meta-analysis
2012, International Journal of Radiation Oncology Biology PhysicsA review of recently published radiotherapy treatment guidelines for bone metastases: Contrasts or convergence?
2012, Journal of Bone OncologyCitation Excerpt :The patient in variant number 4 has previously received palliative radiotherapy for a site of painful bony disease with a good initial response, though their pain has recurred and the panel was tasked with evaluating the safety and efficacy of EBRT re-treatment to the same painful site. The panel described the available re-treatment data as being of low quality because it was mostly retrospective, single-institutional, and dated [13–18]. Given those limitations, the group recommended caution when treating volumes containing normal tissue structures which might suffer side effects from the combined palliative doses.
Internal radiotherapy of painful bone metastases
2011, MethodsCitation Excerpt :Commonly used regimes include 30 Gy in 10 fractions or 20 Gy in five fractions [89]. Controversy exists regarding whether single- or multiple fraction radiotherapy is superior [90], with some trials indicating that single-fraction therapy could be as effective (both in pain relief and duration of response) as multiple-fraction therapy [91–93], other trials have demonstrated that higher doses of radiation were more effective, particularly for patients with a relatively good prognosis [94–97]. Other trials revealed no differences between the two schedules [98].
Radiation Therapy for Cancer Pain Management
2006, Cancer Pain: Pharmacological, Interventional, and Palliative Care ApproachesRhemium-186-monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation
2006, Nuclear Medicine and Biology