Elsevier

Phytochemistry

Volume 10, Issue 7, July 1971, Pages 1579-1582
Phytochemistry

Trans-trans-3,11-tridecadiene-5,7,9-triyne-1,2-diol, an antifungal polyacetylene from diseased safflower (Carthamus tinctorius)

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Abstract

Safflower plants (Carthamus tinctorius L.) were wound-inoculated with Phytophthora drechsleri Tucker, a fungus which incites a root and stem-rot disease of cultivated safflower. Extracts of diseased hypocotyls were highly toxic to the linear growth of the pathogen. The major toxic compound was isolated from the extracts and identified with the aid of u.v., i.r. and mass spectroscopy as trans-trans-3,11-tridecadiene-5,7,9-triyne-1,2-diol.

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