ArticleSuppression of feeding and body weight by inescapable shock: Modulation by quinine adulteration, stress reinstatement, and controllability
References (45)
- et al.
Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty
Life Sci.
(1982) - et al.
Brain norepinephrine depleting lesions selectively enhance behavioral responsiveness to novelty
Physiol. Behav.
(1984) - et al.
A dissociation of the effects of control and prediction
Learn. Motiv.
(1988) - et al.
Effects of stressors in the learned helplessness paradigm on body weight and taste aversion in rats
Physiol. Behav.
(1988) Predictable versus unpredictable shock: Preference behavior and stomach ulceration
Physiol Behav.
(1972)- et al.
The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats
Brain Res.
(1978) - et al.
Learned helplessness: An experimental model of the DST in rats
Biol. Psychiatry
(1988) Animal model of depression: Pharmacological sensitivity of a hedonic deficit
Pharmacol. Biochem. Behav.
(1982)Set points and body weight regulation
Psychiatr. Clin. North Am.
(1978)- et al.
Learned helplessness: All of us were right (and wrong): Inescapable shock has multiple effects
Serial stressors: Prior exposure to a stressor modulates its later effectiveness on gastric ulceration and corticosterone release
Behav. Neural Biol.
Absence of glucoprivic feeding after stress suggests impairment of noradrenergic neuron function
Brain Res.
Effects of quinine adulterated diets on the food intake and body weight of obese and non-obese hypothalamic hyperphagic rats
Physiol. Behav.
Validation criteria for animal models of human mental disorders: Learned helplessness as a paradigm case
Prog. Neuropsychopharmacol. Biol. Psychiatry
Diagnostic and statistical manual of mental disorders
Effect of inescapable shock on subsequent escape performance: Catecholaminergic and cholinergic mediation of response initiation and maintenance
Psychopharmacology
Catecholamine depletion upon reexposure to stress: Mediation of escape deficits produced by inescapable shock
J. Comp. Physiol. Psychol.
Depression: The predisposing influence of stress
Brain Behav. Sci.
Deleterious effects of anxiety elicited by conditioned pre-aversive stimuli in the rat
Psychosom. Med
Sensory pleasure
Q. Rev. Biol.
Inescapable shock increases finickiness about drinking quinine-adulterated water in rats
Learn. Motiv.
Learned helplessness, inactivity, and associative deficits: Effects of inescapable shock on response choice learning
Cited by (53)
Are periaqueductal gray and dorsal raphe the foundation of appetitive and aversive control? A comprehensive review
2019, Progress in NeurobiologyCitation Excerpt :Later investigations found the same results in cats, rats, fish and humans. In rodents, for example, the presentation of a repeated, inescapable and aversive stimulus causes long-term reductions in general responsiveness: reducing social interaction (Short and Maier, 1993) and sexual performance (Holmer et al., 2003), reducing food intake (Dess et al., 1989); and causing weight loss even when control and shocked rats consume the same number of calories, indicating changes in metabolic rate (Dess et al., 1988). The phenomenology of learned helplessness in animals resembles the symptomology of depression in humans: a general reduction of pleasure or interest in activities, change in appetite, diminished sexual libido (Mathew and Weinman, 1982) and social interaction (Hirschfeld et al., 2000).
Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats
2013, NeuropharmacologyCitation Excerpt :Here, we examined the involvement of mGlu5 receptors in congenitally learned helpless (cLH) rats, which provide a genetic animal model of depression. Learned helplessness to uncontrollable and unpredictable stress is an established model of major depression with excellent construct and face validity (Seligman et al., 1975; Dess et al., 1988, 1989; Adrien et al., 1991; Willner, 1995; Henn and Vollmayr, 2005; Chourbaji et al., 2005). cLH and cNLH (congenitally not learned helpless = resilient) rats have been developed by selectively breeding learned helpless and not learned helpless animals, respectively, for more than 60 generations.
Prazosin administered prior to inescapable stressor blocks subsequent exaggeration of acoustic startle response in rats
2007, Pharmacology Biochemistry and BehaviorThe taste of sickness: Lipopolysaccharide-induced finickiness in rats
2005, Physiology and BehaviorRats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning
2004, Behavioural Brain ResearchSerum cholesterol levels and stressor controllability in rats
2003, Physiology and Behavior