Elsevier

Clinica Chimica Acta

Volume 77, Issue 1, 16 May 1977, Pages 83-89
Clinica Chimica Acta

Serum γ-glutamyl transferase activity in chronic renal failure during regular heamodialysis and after successful renal transplantation

https://doi.org/10.1016/0009-8981(77)90405-3Get rights and content

Abstract

Serum γ-glutamyl transferase activity (γ-GT) was measured in 108 uraemic patients, 110 patients on regular haemodialysis and 71 successfully transplanted patients. The incidence of abnormal results was 11, 14 and 28%, respectively. The results in the non-dialyzed and dialyzed patients indicate that in uraemia serum γ-GT activity remains normal and as such, significant hepatic microsomal enzyme induction does not appear to occur. Raised serum γ-GT in uraemic patients and after renal transplantation should suggest concurrent, added, pathology such as hepatobiliary disease or the administration of hepatic microsomal enzyme inducing drugs.

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Cited by (5)

∗

Present address: Department of Nephrology, Mayo Clinic, Rochester, Minn. 55901 U.S.A.

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