Regular paperLipid modulation of nicotinic acetylcholine receptor function: the role of membrane lipid composition and fluidity
References (17)
Biochim. Biophys. Acta
(1985)- et al.
J. Biol. Chem.
(1984) - et al.
Neuroscience
(1982) - et al.
Biochim. Biophys. Acta
(1992) - et al.
Biochim. Biophys. Acta
(1989) - et al.
Biochemistry
(1985) - et al.
Biochemistry
(1990) - et al.
Biochemistry
(1986)
There are more references available in the full text version of this article.
Cited by (107)
Boundary lipids of the nicotinic acetylcholine receptor: Spontaneous partitioning via coarse-grained molecular dynamics simulation
2019, Biochimica et Biophysica Acta - BiomembranesCommon binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel
2019, Biochimica et Biophysica Acta - Molecular and Cell Biology of LipidsHow lipids contribute to ion channel function, a fat perspective on direct and indirect interactions
2018, Current Opinion in Structural BiologyLangmuir-monolayer methodologies for characterizing protein-lipid interactions
2018, Chemistry and Physics of LipidsReconstitution of Ion Channels in Planar Lipid Bilayers: New Approaches
2018, Advances in Biomembranes and Lipid Self-AssemblyCitation Excerpt :A change in the membrane fluidity must equally alter the rate of the conformational transition in both directions (forward vs backward), since the ratio of that rates is equal to the time-independent equilibrium constant. Indeed, the acetylcholine receptor, a ligand-gated ion channel, exhibited similar ability to function in liposomal membrane of both high and low fluidity [119]. Moreover, this study suggested that the lipid composition plays a more important role in the activity of acetylcholine receptors than the bulk membrane fluidity, as measured by the steady-state anisotropy of two membrane probes controlling the order of different membrane domains.
The Role of Cholesterol in the Activation of Nicotinic Acetylcholine Receptors
2017, Current Topics in Membranes
Copyright © 1994 Published by Elsevier B.V.