Photophobia: Mechanism and Implications*
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Cited by (48)
Light aversion and corneal mechanical sensitivity are altered by intrinscally photosensitive retinal ganglion cells in a mouse model ofcorneal surface damage
2015, Experimental Eye ResearchCitation Excerpt :Photoallodynia (photophobia) is the association of pain, ranging from discomfort to severe pain, with normal and/or low levels of light exposure. It is caused by a vast array of acute or chronic, ocular or brain dysfunction and disease including corneal surface damage from dry eye disease, LASIK, corneal abrasions, inflammation or neuropathy (Lebensohn, 1951; Hollander and Aldave, 2004; Ramaesh et al., 2007; Digre and Brennan, 2012; Matynia and Gorin, 2013). Photoallodynia is difficult to treat in part due to a lack of understanding of the photoreceptive and nociceptive pathways involved.
Posterior hypothalamic modulation of light-evoked trigeminal neural activity and lacrimation
2013, NeuroscienceCitation Excerpt :Enhanced sensitivity to visible light, often referred to as photophobia or photo-oculodynia (Lebensohn, 1951; Digre and Brennan, 2012), causes a wide range of ocular sensations that can vary in intensity from mild discomfort to intolerable pain.
Glare's causes, consequences, and clinical challenges after a century of ophthalmic study
2012, American Journal of OphthalmologyCurrent understanding and treatment of headache disorders: Five new things
2011, NeurologyCitation Excerpt :Migraineurs typically develop worsening pain and migraine symptoms when exposed to light, a phenomenon known as photophobia. Photophobia is also common in ocular disorders, such as iritis19 and uveitis, and intracranial disorders, such as meningitis. In the classic visual pathway, light activates rods and cones in the retina, which activate retinal ganglion cells that project via the optic nerve, to the lateral geniculate nucleus, superior colliculus, and then the visual cortex.
Trigeminal Sensitization in a Closed Head Model for Mild Traumatic Brain Injury
2024, Journal of NeurotraumaCustomized designed notch filters and applied effects on glare and contrast sensitivity in patients with dry eye syndrome
2023, International Ophthalmology
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From the Department of Ophthalmology, Northwestern University Medical School. Read by invitation before the St. Louis Ophthalmic Society, March 2, 1951.