Left ventricular diastolic function in weight lifters
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2018, Mayo Clinic ProceedingsCitation Excerpt :Most of the studies of the effect of anabolic steroid use on the heart have been performed in weightlifters, raising the question of whether exercise represents a confounder in this population. Indeed, one study found that long-term powerlifters had increased wall thickness and left ventricular mass on echocardiography.16 However, whether left ventricular morphology is changed with exercise is not well documented; with the exception of left ventricular mass, the other values were not statistically significant when corrected for the total body mass in the aforementioned study.
Administration of an anabolic steroid during the adolescent phase changes the behavior, cardiac autonomic balance and fluid intake in male adult rats
2014, Physiology and BehaviorCitation Excerpt :Cardiovascular dysfunction, including sudden cardiac death, is one of the main side effects associated with AAS abuse, both in AAS users and animal models of AAS abuse, concomitant with the behavioral changes observed [10–13]. Although several studies have shown direct cardiac changes induced by AAS, including ventricular hypertrophy associated with diastolic dysfunction [14,15], thrombosis and myocardial infarction [16,17], indirect effects of AAS on heart morphology and function are difficult to exclude. Thus, the cause and effect relationship between the heart and other tissues remains unclear in the literature.
Chemical cardiomyopathies: The negative effects of medications and nonprescribed drugs on the heart
2011, American Journal of MedicineCitation Excerpt :Anabolic steroids can cause hypertension, dyslipidemia, and impaired fasting glucose.23 Anabolic steroids can cause alterations in heart structure, including left ventricular hypertrophy and dilation, and impaired contraction and relaxation.24,25 Potential sequelae include hypertension, arrhythmias, heart failure, myocardial infarction, and sudden death.
Anabolics and Cardiomyopathy in a Bodybuilder: Case Report and Literature Review
2009, Journal of Cardiac FailureCitation Excerpt :Such changes are more noticeable in bodybuilders than weightlifters because the type of exercises bodybuilders do increases stroke volume and cardiac output to a greater degree than in other athletes. According to Pearson et al,19 weight lifters had significantly higher LV end-diastolic volume, dimension, and posterior wall thickness when compared with normal-active matched control subjects; however, a correction for body surface area resulted in no significant difference in these values. Still, LV mass index was increased in weight lifters, pointing toward alterations of LV morphology.
Cardiac structure and function in resistance-trained and untrained adults: A systematic review and meta-analysis
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