Intestinal Autotransplantation and In-Situ Resection of Recurrent Pancreatic Head Intraductal Tubulopapillary Neoplasm with Portal Cavernoma: A Case Report
Section snippets
Patient Presentation
This report was exempt from an institutional review board approval. The patient was a 24-year-old Israeli man, who 5 years earlier had undergone distal pancreatectomy and splenectomy for ITPN with multifocal high-grade dysplasia. Nearly 30 months later, he developed abdominal pain, diarrhea, exocrine pancreatic insufficiency, diabetes, and bouts of sepsis. Computerized tomography (CT) scan showed a recurrent cystic tumor arising from the head of the pancreas. During preoperative workup for
Discussion
Because of its rarity, limited data are available concerning the natural history of ITPN. Malignant transformation with locally invasive disease was found in 54% of ITPNs and was more common in the presence of a large tumor size and a high Ki-67 proliferative index [6]. Similar to other precancerous pancreatic neoplasia, radical, margin-free resection is indicated for premalignant ITPN and ITPN-associated invasive carcinoma [7,8]. In patients with invasive disease, 5-year survival is 71%, and
REFERENCES (15)
- et al.
Intestinal and multivisceral autotransplantation for tumors of the root of the mesentery: long-term follow-up
Surgery
(2012) - et al.
What is transplant oncology?
Surgery
(2019) - et al.
Ex vivo resection and autotransplantation for pancreatic neoplasms
Surg Clin North Am
(2018) - et al.
Partial abdominal evisceration, ex vivo resection, and intestinal autotransplantation for the treatment of pathologic lesions of the root of the mesentery
J Am Coll Surg
(2003) - et al.
Clinical and nutritional outcomes after intestinal autotransplantation
Surgery
(2016) - et al.
[Ex situ operation on the liver. A new possibility in liver surgery]
Langenbecks Arch Chir
(1988) - et al.
Ex vivo pancreaticoduodenectomy and liver autotransplantation for pancreatic head tumor with extensive involvement of the hepatoduodenal ligament
Liver Transpl
(2015)