From the academy
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics

https://doi.org/10.1016/j.jaad.2008.02.039Get rights and content

Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this first of 5 sections of the guidelines of care for psoriasis, we discuss the classification of psoriasis; associated comorbidities including autoimmune diseases, cardiovascular risk, psychiatric/psychologic issues, and cancer risk; along with assessment tools for skin disease and quality-of-life issues. Finally, we will discuss the safety and efficacy of the biologic treatments used to treat patients with psoriasis.

Abbreviations used

AAD
American Academy of Dermatology
BMI
body mass index
BSA
body surface area
CHF
congestive heart failure
CyA
cyclosporine
FDA
Food and Drug Administration
IL
interleukin
LFA
lymphocyte function associated antigen
MS
multiple sclerosis
NB
narrowband
PASI
Psoriasis Area and Severity Index
PASI-75
75% improvement in the Psoriasis Area and Severity Index score
PGA
Physicians Global Assessment
PUVA
psoralen plus ultraviolet A
QOL
quality of life
TB
tuberculosis
TNF
tumor necrosis factor
UV
ultraviolet

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