European Journal of Cancer and Clinical Oncology
Volume 26, Issue 10, 1990, Pages 1049-1054
Specialist interest articleIs placental alkaline phosphatase (PLAP) a useful marker for seminoma?
References (33)
Clinical and biological significance of a isoenzyme tumor marker—PLAP
Clin Biochem
(1987)- et al.
Preliminary observations on the application of carcino-placental alkaline phosphatase to the investigations of patients with seminoma of the testes
Clin Biochem
(1985) - et al.
Evaluation of an amplified enzyme-linked immunoassay of placental alkaline phosphatase in testicular cancer
Eur J Cancer Clin Oncol
(1985) - et al.
Gonadotrophin-producing seminoma: A distinct category of germ cell neoplasm
Clin Radiol
(1982) - et al.
Lactate dehydrogenase as a tumour marker for testicular germ-cell tumours
Eur J Cancer Clin Oncol
(1986) - et al.
Seminoma of the testes: Results of treatment and pattern of failure after radiation therapy
Int J Radiat Oncol Biol Phys
(1982) - et al.
A study of post-orchiectomy surveillance in stage I testicular seminoma
J Urol
(1989) - et al.
An automated technique for segregating populations with a high incidence of Regan isoenzyme in serum
Clin Chim Acta
(1971) - et al.
Catalytic and immunologic activities of placental-like alkaline phosphatase in clinical studies
Electrophoresis of human alkaline and acid phosphatases
Clin Lab Med
(1986)
Radiotherapy for testicular seminoma stage I: Treatment results and long-term post-irradiation morbidity in 365 patients
Int J Radiat Oncol Biol Phys
(1989)
Radiation therapy of seminoma: 17-year experience at the Joint Center for Radiation-Therapy
Radiother Oncol
(1989)
Multicenter evaluation of human placental alkaline phosphatase as a possible tumor-associated antigen in serum
Clin Chem
(1988)
Placental-like alkaline phosphatase
Monoclonal antibody assay of serum placental alkaline phosphatase in the monitoring of testicular tumours
Br J Cancer
(1985)
Serum placental-like alkaline phosphatase (PLAP): a novel combined enzyme linked immunoassay for monitoring ovarian cancer
J Clin Pathol
(1989)
Cited by (37)
Testicular Cancer
2015, Clinical Radiation OncologyCurrent and future biologic markers for disease progression and relapse in testicular germ cell tumors: A review
2014, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :Serum concentrations of PLAP are increased up to 10-fold in smokers. In a Danish study assessing its value in 236 patients with seminoma, substantial overlap in serum values was seen between smokers and nonsmokers among all stages of disease, with sensitivities and specificities among all patients of 45% and 88%, respectively [18]. With this suboptimal sensitivity and specificity, as well as the limited commercial assays for PLAP, this STM is not routinely utilized in the management of GCTs.
Testicular Cancer
2012, Clinical Radiation Oncology: Third EditionTesticular Cancer
2011, Clinical Radiation Oncology, Third EditionSeminoma: Management and prognosis
2005, Urologic OncologyTestis tumors: Diagnosis and staging
2005, Urologic Oncology
Copyright © 1990 Published by Elsevier Ltd.