Caffeine intensities taste of certain sweeteners: Role of adenosine receptor☆
References (20)
Are methylxanthine effects due to antagonism of endogenous adenosine?
Trends Pharmacol Sci
(1980)- et al.
Multiple receptor sites mediate sweetness: Evidence from cross adaptation
Pharmacol Biochem Behav
(1981) - et al.
Methyl xanthines enhance taste: Evidence for modulation of taste by adenosine receptor
Pharmacol Biochem Behav
(1985) - et al.
Qualitative differences among sweeteners
Physiol Behav
(1979) - et al.
Activation of steroidogenesis and adenylate cyclase by adenosine in adrenal and Leydig tumor cells
J Biol Chem
(1977) - et al.
Blood flow regulation by adenosine in heart, brain, and skeletal muscle
- et al.
Evidence for the proximity of sweet and bitter receptor sites
Nature
(1976) - et al.
Adenosine inhibition of catecholamine-induced increase in force of contraction in guinea-pig atrial and ventricular heart preparations: Evidence against a cyclic AMP- and cyclic GMP dependent effect
J Pharmacol Exp Ther
(1984) - et al.
The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart
J Physiol (Lond)
(1929) - et al.
Sweet taste receptor mechanisms
There are more references available in the full text version of this article.
Cited by (39)
Hydration and self-association of caffeine molecules in aqueous solution: Comparative effects of sucrose and β-cyclodextrin
2009, Spectrochimica Acta - Part A: Molecular and Biomolecular SpectroscopyEffects of chronic administration of caffeine and stress on feeding behavior of rats
2008, Physiology and BehaviorCitation Excerpt :Adenosine is known to modulate the action of neurotransmitters, including dopamine, in the nucleus accumbens [24,25]. Some studies demonstrate that a functional dopamine/adenosine interaction in the nucleus accumbens is necessary to induce the reinforcing effects of rewards [26], and that adenosine is involved in the sweet taste perception [27,28]. Therefore, this modulation could be involved in the present behavioral findings [29].
Investigation of synergism in binary mixtures of sweeteners
1995, Brain Research BulletinMolecular cloning of G proteins and phosphodiesterases from rat taste cells
1994, Physiology and BehaviorMethyl xanthine, adenosine, and human taste responsivity
1992, Physiology and BehaviorSweeteners: State of knowledge review
1993, Neuroscience and Biobehavioral Reviews
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This research was supported by grant NIA AG 00443 and a grant from General Foods Corporation.
Copyright © 1986 Published by Elsevier Inc.