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Glassy carbon electrode modified by gold nanofibers decorated iron metal–organic framework nanocomposite for voltammetric determination of acetaminophen

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Abstract

In this work, a nanocomposite containing gold (Au) nanofibers decorated iron-metal–organic framework (Fe-MOF) was successfully synthesized for electrochemical detection of acetaminophen (AAP). The as-synthesized Au@Fe-MOF nanocomposite was confirmed by various characterization techniques. Morphological analysis showed that the Au nanofibers with an average size of less than 10 nm were dispersed on the Fe-MOF. Cyclic voltammetric analysis showed that the Au@Fe-MOF nanocomposite showed well-defined redox peaks with higher current than that of GCE and Fe-MOF. The Au@Fe-MOF/GCE exhibited a linear range, sensitivity, and detection limit of 0.5–18 µM, 4.95 µM/µA/cm2, and 0.12 µM, respectively. The Au@Fe-MOF/GCE showed a very low response for the interference materials. The real sample analysis revealed that the Au@Fe-MOF/GCE showed good recovery towards the AAP in urine and paracetamol. Therefore, the developed sensor can be used for quality control of AAP.

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Acknowledgements

This study was supported by the Department of Biotechnology, Government of India under Ramalingasami Re-entry Fellowship Scheme (BT/RLF/Re-entry/48/2015).

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Authors and Affiliations

  1. Department of Nanoscience and Technology, Bharathiar University, Coimbatore, Tamilnadu, 641046, India

    K. V. Kavya, Dinesh Muthu, Stella Varghese, Dhanaprabhu Pattappan, R. T. Rajendra Kumar & Yuvaraj Haldorai

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  1. K. V. Kavya
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  2. Dinesh Muthu
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  3. Stella Varghese
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  4. Dhanaprabhu Pattappan
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Correspondence to Yuvaraj Haldorai.

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Kavya, K.V., Muthu, D., Varghese, S. et al. Glassy carbon electrode modified by gold nanofibers decorated iron metal–organic framework nanocomposite for voltammetric determination of acetaminophen. Carbon Lett. 32, 1441–1449 (2022). https://doi.org/10.1007/s42823-022-00373-3

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  • DOI: https://doi.org/10.1007/s42823-022-00373-3

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