Skip to main content

Advertisement

Log in

An Egyptian Study of Sleep Disorders and Its Correlates in End-Stage Renal Disease Patients Receiving Hemodialysis

  • Original Article
  • Published:
Sleep and Vigilance Aims and scope Submit manuscript

Abstract

Background

Various sleep disorders are reported to be frequent in end-stage renal disease (ESRD) patients on hemodialysis. This study aimed to assess the prevalence of sleep disorders and their correlates among hemodialysis patients.

Methodology

This cross-sectional study included 200 recruited ESRD patients on hemodialysis, who were assessed for sleep disorders by administering Pittsburgh sleep quality index, Berlin questionnaire and STOP-BANG for sleep apnea, and International restless legs syndrome study group rating scale.

Results

The mean age of the study sample was 51.7 ± 6 years. Most of the patients were males (66.2%), and 53.2% of participants were governmental employees. The prevalence of hypertension and diabetus were (53.7%, and 13.9% respectively).It was found that 62.2% of the sample were classified as poor sleepers. While 25.9% had EDS and 11.4% had RLS.

Conclusion

Sleep disorders are common but neglected in subjects on hemodialysis. Certain clinical correlates might negatively impact the severity of sleep disorders and thus worsen the dialysis efficiency. Early detection and treatment of sleep disorders in subjects with ESRD might improve the prognosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ahmad S, Gupta M, Gupta R, Dhyani M. Prevalence and correlates of insomnia and obstructive sleep apnea in chronic kidney disease. N Am J Med Sci. 2013;5(11):641.

    Article  Google Scholar 

  2. Ahmadi N, Chung SA, Gibbs A, Shapiro CM. The Berlin questionnaire for sleep apnea in a sleep clinic population: relationship to polysomnographic measurement of respiratory disturbance. Sleep Breathing. 2008;12(1):39–45.

    Article  Google Scholar 

  3. Buysse J, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry res. 1989;28(2):193–213.

    Article  CAS  Google Scholar 

  4. Čengić B, Resić H, Spasovski G, Avdić E, Alajbegović A. Quality of sleep in patients undergoing hemodialysis. Int Urol Nephrol. 2012;44(2):557–67.

    Article  Google Scholar 

  5. Chu G, Choi P, McDonald VM. Sleep disturbance and sleep‐disordered breathing in hemodialysis patients. Seminars in dialysis, Wiley Online Library. 2018.

  6. Chughtai SAS, Afzal BB, Scott JJ, Khan SS, Poyyamazhi RR, Aswad MMG, Yates JJ, Black JJ, Rizello AA, Ali AA. Comparison of sleep quality in hemodialysis vs kidney transplant recipients using pittsburgh sleep quality index (PSQI). Transplantation. 2018;102:S539.

    Article  Google Scholar 

  7. Ezzat H, Mohab A. Prevalence of sleep disorders among ESRD patients. Ren Fail. 2015;37(6):1013–9.

    Article  CAS  Google Scholar 

  8. Fonseca NT, Urbano JJ, Nacif SR, Silva AS, Peixoto RAO, Urbano GJ, Oliveira EF, Santos IR, Oliveira CS, Insalaco G. A systematic review of sleep disorders in patients with chronic kidney disease undergoing hemodialysis. J Phys Therapy Sci. 2016;28(7):2164–70.

    Article  Google Scholar 

  9. Han SH, Lee JE, Kim DK, Moon SJ, Kim H-W, Chang JH, Kim BS, Kang S-W, Choi KH, Lee HY. Long-term clinical outcomes of peritoneal dialysis patients: single center experience from Korea. Perit Dial Int. 2008;28(Supplement 3):S21–S2626.

    Article  Google Scholar 

  10. Hanly PJ, Gabor JY, Chan C, Pierratos A. Daytime sleepiness in patients with CRF: impact of nocturnal hemodialysis. Am J Kidney Dis. 2003;41(2):403–10.

    Article  Google Scholar 

  11. Hanly PJ, Pierratos A. Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysis. N Engl J Med. 2001;344(2):102–7.

    Article  CAS  Google Scholar 

  12. Huang S-T, Lin C-L, Yu T-M, Kao C-H, Liang W-M, Chou T-C. Risk, severity, and predictors of obstructive sleep apnea in hemodialysis and peritoneal dialysis patients. Int J Environ Res Public Health. 2018;15(11):2377.

    Article  Google Scholar 

  13. Iliescu EA, Coo H, McMurray MH, Meers CL, Quinn MM, Singer MA, Hopman WM. Quality of sleep and health-related quality of life in haemodialysis patients. Nephrol Dial Transplant. 2003;18(1):126–32.

    Article  Google Scholar 

  14. Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath. 2008;12(2):161–8.

    Article  Google Scholar 

  15. Johns MW. Daytime sleepiness, snoring, and obstructive sleep apnea: the Epworth Sleepiness Scale. Chest. 1993;103(1):30–6.

    Article  CAS  Google Scholar 

  16. Lara AS, Salomao LPB, Romao APMS, Reis RM, Navarro PA, Rosa-e-Silva J, Carolina A, Ferriani RA. Effect of infertility on the sexual function of couples: state of the art. Recent Patents Endocr Metab Immune Drug Discov. 2015;9(1):46–53.

    Article  CAS  Google Scholar 

  17. Manconi M, Ulfberg J, Berger K, Ghorayeb I, Wesström J, Fulda S, Allen RP, Pollmächer T. When gender matters: restless legs syndrome. Report of the “RLS and woman” workshop endorsed by the European RLS Study Group. Sleep Med Rev. 2012;16(4):297–307.

    Article  Google Scholar 

  18. Mehrabi S, Sarikhani S, Roozbeh J. Sleep quality in patients undergoing long-term hemodialysis using the Pittsburgh sleep quality index. Nephro-Urol Mon. 2017;9(2):e13137. https://doi.org/10.5812/numonthly.44278.

    Article  Google Scholar 

  19. Salahuddin M, Maru TT, Kumalo A, Pandi-Perumal SR, Bahammam AS, Manzar MD. Validation of the Pittsburgh sleep quality index in community dwelling Ethiopian adults. Health Qual Life Outcomes. 2017;15(1):58.

    Article  Google Scholar 

  20. Shafi ST, Shafi T. A comparison of quality of sleep between patients with chronic kidney disease not on hemodialysis and end-stage renal disease on hemodialysis in a developing country. Ren Fail. 2017;39(1):623–8.

    Article  Google Scholar 

  21. Shen Q, Huang X, Luo Z, Xu X, Zhao X, He Q. Sleep quality, daytime sleepiness and health-related quality-of-life in maintenance haemodialysis patients. J Int Med Res. 2016;44(3):698–709.

    Article  Google Scholar 

  22. Tomita T, Yasui-Furukori N, Oka M, Shimizu T, Nagashima A, Mitsuhashi K, Saito H, Nakamura K. insomnia in patients on hemodialysis for a short versus long duration. Neuropsychiatr Dis Treat. 2016;12:2293.

    Article  Google Scholar 

  23. Unruh ML, Larive B, Eggers PW, Garg AX, Gassman JJ, Finkelstein FO, Kimmel PL, Chertow GM, Group FT, Achinger S. The effect of frequent hemodialysis on self-reported sleep quality: frequent hemodialysis network trials. Nephrol Dial Transplant. 2016;31(6):984–91.

    Article  Google Scholar 

  24. Walsh M, Manns BJ, Klarenbach S, Tonelli M, Hemmelgarn B, Culleton B. The effects of nocturnal compared with conventional hemodialysis on mineral metabolism: a randomized-controlled trial. Hemodial Int. 2010;14(2):174–81.

    Article  Google Scholar 

Download references

Acknowledgements

We acknowledge the time and efforts of the participants who agreed to take part in the study despite their medical status and dialysis consequences. We also appreciate the efforts of the nursing staff members at the study sites in facilitating the mission of the research team.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nevin F. W. Zaki.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kamal, M., Zaki, N.F.W., Yousef, E.A. et al. An Egyptian Study of Sleep Disorders and Its Correlates in End-Stage Renal Disease Patients Receiving Hemodialysis. Sleep Vigilance 4, 213–220 (2020). https://doi.org/10.1007/s41782-020-00095-4

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s41782-020-00095-4

Keywords

Navigation