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An Ultrasound-Promoted Efficient Synthesis of New 4-Hydroxy-2(1H)-quinolone-Derived Amino Nitrile Pyridines

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Abstract

Ultrasound-promoted efficient synthesis of new compounds 2-amino-6-(1, 2-dihydro-4-hydroxy-2-oxoquinolin-3-yl)-4-arylpyridine-3-carbonitriles (4ap) from 4-hydroxy-3-((E)-3-arylacryloyl) quinolin-2(1H)-ones (3ap) has been described. The effect of solvent and ultrasound irradiation has been described.

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Acknowledgements

We thank Mr. BRS Rao (Managing Director of LGC Promochem Private Limited, Bangalore) for his financial support. We thank VIT-SIF Vellore for providing NMR facility and SAIF-IIT Madras, Chennai for providing HR-MS analytical service.

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Correspondence to S. Sarveswari.

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Alla, K., Sarveswari, S. An Ultrasound-Promoted Efficient Synthesis of New 4-Hydroxy-2(1H)-quinolone-Derived Amino Nitrile Pyridines. Iran J Sci Technol Trans Sci 43, 465–475 (2019). https://doi.org/10.1007/s40995-018-0567-z

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