Abstract
Introduction
Fibroblastic reticulum cell tumor (FRCT) is a rare tumor arising from the antigen-presenting dendritic cells.
Method
We present a case of FRCT of breast in a 62-year-old female, who presented with a right breast lump. Computed tomography scan revealed a well-circumscribed right breast mass. There was no axillary lymph node enlargement or distant metastasis.
Result
The patient had localized disease and underwent simple mastectomy followed by adjuvant chemotherapy. The patient is well and disease free at the end of 2 years of follow-up. Only two cases of FRCT of breast have been reported in the literature.
Conclusion
FRCT can be misdiagnosed as phyllodes tumor, anaplastic large cell lymphoma and carcinoma. There is no consensus on the role of adjuvant chemotherapy or radiotherapy in FRCT of breast due to paucity of data.
Similar content being viewed by others
References
Chan AC, Serrano-Olmo J, Erlandson RA, Rosai J. Cytokeratin-positive malignant tumors with reticulum cell morphology: a subtype of fibroblastic reticulum cell neoplasm? Am J Surg Pathol. 2000;24:107–16.
Balogh P, Fisi V, Szakal AK. Fibroblastic reticular cells of the peripheral lymphoid organs: unique features of a ubiquitous cell type. Mol Immunol. 2008;46:1–7.
Li H, Shen P, Liang Y, Zhang F. Fibroblastic reticular cell tumor of the breast: a case report and review of the literature. Exp Ther Med. 2016;11:561–4.
Sundersingh S, Majhi U, Krishnamurthy A, Velusami SD. Cytokeratin-positive interstitial reticulum cell sarcoma: extranodal presentations mimicking carcinoma. Indian J Pathol Microbiol. 2013;56:172–5.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
None.
Human and Animal Rights
This article does not contain any studies with human participants or animals performed by any of the authors.
Informed Consent
Informed consent has been obtained.
Rights and permissions
About this article
Cite this article
Iyer, P., Sundersingh, S., Venkatesan, E. et al. Fibroblastic Reticulum Cell Tumor of the Breast: A Case Report and Review of Literature. Indian J Gynecol Oncolog 15, 42 (2017). https://doi.org/10.1007/s40944-017-0137-x
Received:
Revised:
Accepted:
Published:
DOI: https://doi.org/10.1007/s40944-017-0137-x