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Factorial Analysis of Variables Influencing Mechanical Characteristics in Le Fort I Osteotomy Using FEA and Statistics-Based Taguchi Method

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Abstract

This study investigated the Le Fort I osteotomy biomedical interactions for multi-factorial parameters (bone healing situation, cortical bone thickness, mini-plate fixation type, and screw length) under oblique load conditions using a nonlinear finite element (FE) approach. Nonlinear FE analysis was used to simulate the screw/plate and plate/bone and the bone healing adaptations with osseous nonunion in Le Fort I osteotomy models. The Taguchi method was used to identify the importance of each parameter and determine an optimal biomechanical response. With respect to relative micro-movement between the two bone segments and the magnitude of the stress values in the mini-plates, the bone healing situation had the dominant effect. The main effect plot showed that osseous nonunion increased the micro-movements and mini-plate stress values. Cortical bone thickness, mini-plate fixation type and screw length did not significantly affect the micro-movement and stress values. The combined use of FE analysis and the Taguchi method facilitated effective Le Fort I osteotomy mechanical characteristics evaluation.

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Acknowledgments

This study in part by MOST Project 103-2221-E-010 -012 -MY3 of the Ministry of Science and Technology, Taiwan and Project CRRPG5C0292 of Chang Gung Memorial Hospital, Tao-yuan, Taiwan.

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Authors and Affiliations

  1. Department of Biomedical Engineering, National Yang-Ming University, 155 Linong Street Sec. 2, Taipei, 112, Taiwan

    Shao-Fu Huang & Chun-Li Lin

  2. Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, 5 Fu-Shin Street, Kwei Shan, Taoyuan, 333, Taiwan

    Lun-Jou Lo

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  1. Shao-Fu Huang
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Correspondence to Chun-Li Lin.

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Huang, SF., Lo, LJ. & Lin, CL. Factorial Analysis of Variables Influencing Mechanical Characteristics in Le Fort I Osteotomy Using FEA and Statistics-Based Taguchi Method. J. Med. Biol. Eng. 36, 495–505 (2016). https://doi.org/10.1007/s40846-016-0157-5

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  • DOI: https://doi.org/10.1007/s40846-016-0157-5

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