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The Advance of Plasmonic-Electric Nanopipette Sensing in Single Cells

  • Nanodrugs (ATY Lau, Section Editor)
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Abstract

Nanopipette provides a promising limited space, which demonstrates achievements in optical, electrochemical, and mass spectral measurements on the nanoscales. It has been applied to uncover the potential properties of populations and dynamics of individual molecules and individual particles. Plasmonic-electric nanopipette tip probe of individual cells provides more accurate diacrisis and grasp of elementary chemical and biological processes. Recent advances in individual cells provide tools for hypersensitive analysis. In this review, we summarize the results of recent progresses in studying nanopipette photonic and electrical probe tips of individual cells. The benefits of confining these optical-electric nanopipette tip probe to a compatible dimension measurement interface are instantiated. Ultimately, the opportunities and challenges of optical-electric nanopipette tip probe of single cell are addressed.

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Funding

We gratefully appreciate the National Natural Science Foundation of China (21904068, 81922041, 81570378, and 81772020); the Science and Technology of Jiangsu Province China (BK20201351, BK20170048); Jiangsu University Natural Science Research Program (19KJB150014, 19KJB340001); and Jiangsu Specially Appointed Professor program, Introduction of talent research start fund of Nanjing Medical University (NMUR2019007).

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  1. Department of Forensic Medicine, Nanjing Medical University, Nanjing, Jiangsu, 211166, People’s Republic of China

    Yue Cao, You-Jia Yu, Qiao-Yan Jiang, Yang Sun, Zhengsheng Mao, Jie Wang & Feng Chen

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  1. Yue Cao
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  2. You-Jia Yu
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Cao, Y., Yu, YJ., Jiang, QY. et al. The Advance of Plasmonic-Electric Nanopipette Sensing in Single Cells. Curr Pharmacol Rep 7, 55–66 (2021). https://doi.org/10.1007/s40495-021-00249-6

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