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The prevalence and predictors of pre-diabetes and diabetes among adults 40–70 years in Kharameh cohort study: A population-based study in Fars province, south of Iran

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Abstract

Purpose

In this study, the prevalence of diabetes and pre-diabetes (pre-DM) has been estimated; also, some factors related to diabetes and pre-diabetes in the city of Kharameh, southern Iran, were investigated.

Methods

This cross-sectional study was conducted on a total of 10,474 subjects aged 40–70 years who participated in phase one of PERSIAN Kharameh cohort carried out between 2015 and 2016. Eligible individuals were included in the study by census method.

Results

Prevalence of diabetes is 20.17% (95% CI: 19.95–20.39) and that of pre-diabetes is 15.74% (95% CI 15.54–15.93). Multivariate logistic regression results showed that the prevalence of diabetes had a direct relationship with increasing age (p < 0.001), being single (p = 0.005), family history of diabetes (p < 0.001), abdominal obesity (p < 0.001), hypertension (p: < 0.001), and high triglycerides (p: < 0.001); also, it had an inverse relationship with residence in rural areas (p < 0.001), education (p < 0.001), and employment (p < 0.001).

Also, the prevalence of pre-diabetes showed a direct relationship with increasing age (60–70 years p = 0.010), being single (p = 0.004), living in rural areas (P < 0.001), having a family history of diabetes ( both P = 0.023), abdominal obesity (P < 0.001), hypertension (P < 0.001), high cholesterol (P < 0.001) and high triglycerides (P < 0.001), and an inverse relationship with female gender (P < 0.001), education (high school P = 0.022), employment (P = 0.010), and smoking habit (P = 0.019). These results were all statistically significant.

Conclusion

The present study shows the high prevalence of diabetes and pre- diabetes in the city of Kharameh. Diabetes prevention policies should be developed and implemented for the public.

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Funding

Shiraz University of Medical Sciences financially supported this study. (Grant number: 99–12-05–21892).

Author information

Authors and Affiliations

  1. Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Masoumeh Ghoddusi Johari

  2. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

    Kimia Jokari

  3. Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Alireza Mirahmadizadeh

  4. Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran

    Mozhgan Seif

  5. Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Abbas Rezaianzadeh

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  1. Masoumeh Ghoddusi Johari
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  2. Kimia Jokari
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Correspondence to Kimia Jokari.

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The study protocol was reviewed and approved by the ethical committee of Shiraz University of Medical Sciences (approval number: IR.SUMS.REC.1399.1266).

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Johari, M.G., Jokari, K., Mirahmadizadeh, A. et al. The prevalence and predictors of pre-diabetes and diabetes among adults 40–70 years in Kharameh cohort study: A population-based study in Fars province, south of Iran. J Diabetes Metab Disord 21, 85–95 (2022). https://doi.org/10.1007/s40200-021-00938-5

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