Abstract
Ayurvedic nano-medicine preparations (ANMPs), Bhasma and Sindura, are considered as most effective dosage forms in Ayurveda. These are the preparations of metals and minerals used for therapeutic purposes in Ayurveda. Those are prepared by repeated trituration with liquid media from plant materials and incineration at high temperature above 650°C. These preparations are claimed as biologically produced nano-medicines formed by metallic/mineral nanoparticles. Presence of carbonaceous nano-materials is also reported in these preparations, in the form of fullerene and others. The complexes of metallic/mineral nanoparticles with carbonaceous nano-materials are formed by the processes of physisorption and chemisorption. The carbonaceous nano-materials are reported to have different biological effects. The ANMPs are safe and are having various biological activities, i.e., antioxidant, immunomodulatory, anti-inflammatory, antitumor, antibacterial, and others. These biological activities of ANMPs are due to the presence of nano-metal or mineral particles conjugated with carbonaceous nano-materials. The conjugation of metals and minerals nanoparticles with nano-carbons makes these preparations biologically safe and therapeutically more effective. Probable effects of the carbonaceous nano-materials present in the ANMPs are discussed in this review.
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Sarkar, P.K., Wele, A. Presence and activities of carbonaceous nano-materials in Ayurvedic nano-medicine preparations. Int Nano Lett 13, 41–51 (2023). https://doi.org/10.1007/s40089-022-00383-z
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DOI: https://doi.org/10.1007/s40089-022-00383-z