Abstract
Acute focal bacterial nephritis (AFBN) is a rare, acute focal infection of the renal parenchyma without liquefaction. The pathogenesis is thought to be due to hematogenous infection or ascending infection from the lower urinary tract. Escherichia coli has been the major pathogen isolated in prior cases, but other Gram-negative enteric pathogens and Staphylococcus aureus have been reported as well. It is well described in children and adults with diabetes and organ transplantation, but has not been previously reported in healthy adults. We report a case of an immunocompetent adult female who presented with a methicillin-resistant Staphylococcus aureus bacteremia after a skin and soft tissue infection that resulted in AFBN.
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Conflict of interest
The authors have no financial conflicts of interest to report. This manuscript was reviewed by the Naval Medical Center San Diego Institutional Review Board prior to submission, but formal ethical approval was not required. NA, MDJ, and RCM are employees of the United States Government. This work was prepared as part of their official duties. Title 17 U.S.C. §105 provides that ‘Copyright protection under this title is not available for any work of the United States Government.’ Title 17 U.S.C. §101 defines a US Government work as a work prepared by a military service member or employee of the US Government as part of that person’s official duties. The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, the Department of Defense, nor the US Government.
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Adams, N., Johnson, M.D., Storm, D.W. et al. Acute focal bacterial nephritis due to methicillin-resistant Staphylococcus aureus in an immunocompetent adult. Infection 42, 433–436 (2014). https://doi.org/10.1007/s15010-013-0553-5
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DOI: https://doi.org/10.1007/s15010-013-0553-5