Abstract
Coccidioidomycosis is an endemic disease of the western hemisphere. In cases occurring in non-endemic areas, eliciting a history of exposure as well as a high index of suspicion is imperative for timely and accurate diagnosis. In this case, a 65-year-old male presented to our hospital with fever, dry cough and malaise, and on X-ray chest, was found to have a lower lobe consolidation left lung with nodular lesions in both lungs and necrotic mediastinal lymphadenopathy. He lived in Arizona, USA, for 6 months before admission. Pulmonary coccidioidomycosis was confirmed by the isolation of Coccidioides spp. in pure culture from both broncho-alveolar lavage and lung biopsy specimens. The identity of the isolate was confirmed as C. posadasii by gene sequencing. The patient improved after being treated with fluconazole.
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Acknowledgments
We wish to thank Prof. Arunaloke Chakrabarti, In-Charge Mycology Division, Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India, for the gene sequencing of the isolate as Coccidioides posadasii.
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Oberoi, J.K., Wattal, C., Aggarwal, P.K. et al. Pulmonary coccidiomycosis in New Delhi, India. Infection 40, 699–702 (2012). https://doi.org/10.1007/s15010-012-0315-9
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DOI: https://doi.org/10.1007/s15010-012-0315-9