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Acute autonomic dysregulation due to HHV-6 encephalitis in an immunocompromised patient: a case report and literature review

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Abstract

Human herpesvirus-6 (HHV-6), in particularly HHV-6B, can reactivate in immunocompromised patients. Especially after stem cell transplantation, reactivation of HHV-6 can cause complications, such as limbic encephalitis. We present a case of a 61-year-old man with B-cell non-Hodgkin lymphoma. He presented with subacute lethargy, confusion and hyperhidrosis. Following this, we will give a short review of the literature considering clinical and technical features as well as treatment options.

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Author information

Authors and Affiliations

  1. Department of Neurology, Jessa Hospital, Stadsomvaart 11, B-3500, Hasselt, Belgium

    Louise Maes & Koen Delmotte

  2. Department of Hematology, Jessa Hospital, Hasselt, Belgium

    Koen Theunissen

  3. Department of Radiology, Jessa Hospital, Hasselt, Belgium

    Steven Schepers & Inge Indesteege

Authors
  1. Louise Maes
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  2. Koen Theunissen
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  3. Steven Schepers
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  4. Inge Indesteege
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  5. Koen Delmotte
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Contributions

LM wrote the initial draft. KD, SS and IE provided critical comments for the final manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Louise Maes.

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The authors report no disclosures relevant to the manuscript.

Ethical approval

Ethical approval was not required for this study as all procedures performed were part of routine clinical care.

Informed consent

The patient’s spouse provided written informed consent for the publication of his anonymized data.

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Maes, L., Theunissen, K., Schepers, S. et al. Acute autonomic dysregulation due to HHV-6 encephalitis in an immunocompromised patient: a case report and literature review. Acta Neurol Belg 122, 583–585 (2022). https://doi.org/10.1007/s13760-021-01828-6

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  • DOI: https://doi.org/10.1007/s13760-021-01828-6

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