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A modified single-walled carbon nanotubes/carbon-ceramic electrode for simultaneous voltammetric determination of paracetamol and caffeine

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Abstract

A simple and sensitive differential pulse voltammetry (DPV) procedure, based on a simple modified electrode; carbon-ceramic electrode (CCE) modified with a thin film of single-walled carbon nanotubes (SWCNT), for the simultaneous determination of paracetamol (PC) and caffeine (CAF) was developed. The SWCNT/CCE displayed excellent electrochemical catalytic activities toward PC and CAF oxidation compared with bare CCE. In DPV technique both PC and CAF give sensitive oxidation peaks at 0.71 and 1.38 V vs. saturated calomel electrode, and under the optimized experimental conditions PC and CAF show linear response over the concentration ranges of 0.08–200.0 μM (R 2 = 0.991) and 0.41–300.0 μM (R 2 = 0.990), respectively. The limits of detection (S/N = 3) for PC and CAF were 0.05 and 0.29 μM, respectively. The investigated method showed good stability, reproducibility, repeatability, and high recovery in some real samples.

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Acknowledgments

The authors gratefully acknowledge the research council of Azarbaijan Shahid Madani University for financial support.

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  1. Electroanalytical Chemistry Laboratory, Department of Chemistry, Faculty of Sciences, Azarbaijan Shahid Madani University, 53714-161, Tabriz, Iran

    Biuck Habibi, Mojtaba Jahanbakhshi & Mehri Abazari

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Habibi, B., Jahanbakhshi, M. & Abazari, M. A modified single-walled carbon nanotubes/carbon-ceramic electrode for simultaneous voltammetric determination of paracetamol and caffeine. J IRAN CHEM SOC 11, 511–521 (2014). https://doi.org/10.1007/s13738-013-0324-3

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