Abstract
A novel MCM/ZrO2 nanoparticles modified carbon paste electrode (MZ-CPE) was fabricated and used to study the electro oxidation of epinephrine (EP) and acetaminophen (AC) and their mixtures by electrochemical methods. The modified electrode showed electrocatalytic activity toward EP and AC oxidation with a decrease of the overpotential by 173 mV to a less positive potential for EP at the surface of the MZ-CPE and an increase in peak current at pH 7.0. Differential pulse voltammetry peak currents of EP and AC increased linearly with their concentrations in the ranges of 1.0 × 10−6–2.5 × 10−3 and 1.0 × 10−6–2.0 × 10−3 M, respectively, and the detection limits for EP and AC were 5.0 × 10−7 and 4.5 × 10−7 M, respectively.
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M. Mazloum-Ardakani, H. Beitollahi, M.A. Sheikh Mohseni, A. Benvidi, H. Naeimi, M. Nejati Barzoki, N. Taghavinia, Colloids Surf B 76, 82 (2010)
M. Hamadanian, A. Reisi-Vanani, A. Majedi, J Iran Chem Soc 7, S52 (2010)
M. Mazloum-Ardakani, M.A. Sheikh-Mohseni, in Carbon nanotubes in electrochemical sensors, ed. by M. Naraghi (InTech, Croatia, 2011)
H. Parham, N. Rahbar, J Hazard Mater 177, 1077 (2010)
M. Mazloum-Ardakani, H. Beitollahi, M.A. Sheikh-Mohseni, H. Naeimi (2011) J Iran Chem Soc 9, 27 (2012)
W. Sun, D. Wang, Z. Zhai, R. Gao, K. Jiao, J. Iran. Chem. Soc. 6, 412 (2009)
W.A. Banks, Brain Res 899, 209 (2001)
L.T. Rong, S.Y. Zen, T.Y. Ching, T.T. Chuan, L.C. Chiun, Biosens Bioelectron 21, 901 (2005)
V. Carrera, E. Sabater, E. Vilanova, M.A. Sogorb, J Chromatogr B 847, 88 (2007)
S. Wei, G. Song, J.M. Li, J Chromatogr A 1098, 166 (2005)
J.X. Du, L.H. Shen, J.R. Lu, Anal Chim Acta 489, 183 (2003)
P. Solich, C.K. Polydorou, M.A. Koupparis, C.E. Efstathiou, J Pharm Biomed Anal 22, 781 (2000)
H. Jeong, H. Kim, S. Jeon, Microchem J 78, 181 (2004)
Y.X. Sun, S.F. Wang, X.H. Zhang, Sens Actuators B 113, 156 (2006)
H. Beitollahi, M. Mazloum-Ardakani, B. Ganjipour, H. Naeimi, Biosens Bioelectron 24, 362 (2008)
M. Mazloum-Ardakani, H. Beitollahi, M.A. Sheikh-Mohseni, H. Naeimi, N. Taghavinia, Appl Catal A Gen 378, 195 (2010)
B.D. Clayton, Y.N. Stock, Basic pharmacology for nurses (Mosby Inc. Harcourt Health Sciences Company, St. Louis, 2001)
M.A. Fotopoulou, P.C. Loannou, Anal Chim Acta 462, 179 (2002)
M.H. Sorouraddin, J.L. Manzoori, E. Kargarzadeh, A.M. Haji Shabani, J Pharm Biomed Anal 18, 877 (1998)
M. Mazloum-Ardakani, H. Beitollahi, M.K. Amini, F. Mirkhalaf, M. Abdollahi-Alibeik, Anal Methods 3, 673 (2011)
A.J. Bard, L.R. Faulkner, Electrochemical methods: fundamentals and applications, 2nd edn. (Wiley, New York, 2001)
E. Akyilmaza, M. Turemisa, I. Yasa, Biosens Bioelectron 26, 2590 (2011)
F. Wang, D. Du, Q.C. Zou, Talanta 57, 687 (2002)
R.M.D. Carvalho, R.S. Freire, S. Rath, L.T. Kubota, J Pharm Biomed Anal 34, 871 (2004)
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The authors wish to thankful the Yazd University Research Council, IUT Research Council and Excellence in Sensors for financial support of this research.
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Mazloum-Ardakani, M., Dehghani-Firouzabadi, A., Rajabzade, N. et al. MCM/ZrO2 nanoparticles modified electrode for simultaneous and selective voltammetric determination of epinephrine and acetaminophen. J IRAN CHEM SOC 10, 1–5 (2013). https://doi.org/10.1007/s13738-012-0121-4
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DOI: https://doi.org/10.1007/s13738-012-0121-4