Skip to main content
Log in

Prehabilitation for High-Risk Surgical Patients

  • Surgical Care (F Luchette, Section Editor)
  • Published:
Current Geriatrics Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Prehabilitation of high-risk surgical patients is an evolving area. The purpose of this review is to describe the scope of prehabilitation programs and their impact on surgical outcomes.

Recent Findings

Prehabilitation interventions optimize a patient for surgery improving physical capabilities, focusing on strengthening respiratory mechanics, enhancing nutrition, and boosting mental strength. There is great variation on how prehabilitation programs are implemented leading to mixed results. The research, specifically in the geriatric population, is promising with a reduction in postoperative complications including mortality.

Summary

An optimal prehabilitation program should meet the needs of the specific patient population. Based on the available literature, a prehabilitation algorithm that focuses on enhancing a patient’s physical, nutritional, and mental status prior to surgery is proposed. Larger studies are needed to evaluate the impact of prehabilitation programs in high-risk geriatric patients and surgical outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Kow AW. Prehabilitation and Its Role in Geriatric Surgery. Ann Acad Med Singap. 2019;48(11):386–92 PMID: 31960020. • Provides updated evidence regarding use of prehabilitation programs in geriatric patients and outcomes. This review looks at the full spectrum of prehabiliation including exercise programs, nutritional interventions, and psychological support.

    PubMed  Google Scholar 

  2. Borrell-Vega J, Esparza Gutierrez AG, Humeidan ML. Multimodal Prehabilitation Programs for Older Surgical Patients. Anesthesiol Clin. 2019;37(3):437–52. https://doi.org/10.1016/j.anclin.2019.04.004 Epub 2019 Jun 26. PMID: 31337477. • Provides an overview of the benefits of prehabilitation programs specifically in the geriatric population and high-risk patients. Reviews current models of prehabiliation starting with exercise-based programs and expanding to include nutritional and behavioral aspects.

    Article  PubMed  Google Scholar 

  3. Liu C, Lu Z, Zhu M, Lu X. Trimodal prehabilitation for older surgical patients: a systematic review and meta-analysis. Aging Clin Exp Res. 2021. https://doi.org/10.1007/s40520-021-01929-5 Epub 2019 Jun 25. PMID: 31248644.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Hanna K, Ditillo M, Joseph B. The role of frailty and prehabilitation in surgery. Curr Opin Crit Care. 2019;25(6):717–22. https://doi.org/10.1097/MCC.0000000000000669 PMID: 31689246. • Provides an overview of frailty and the role of prehabilitation on optimizing outcomes in geriatric patients.

    Article  PubMed  Google Scholar 

  5. Barberan-Garcia A, Ubré M, Roca J, Lacy AM, Burgos F, Risco R, Momblán D, Balust J, Blanco I, Martínez-Pallí G. Personalised Prehabilitation in High-risk Patients Undergoing Elective Major Abdominal Surgery: A Randomized Blinded Controlled Trial. Ann Surg. 2018;267(1):50–6. https://doi.org/10.1097/SLA.0000000000002293 Epub 2015 Apr 14. PMID: 25869228.

    Article  PubMed  Google Scholar 

  6. Tsimopoulou I, Pasquali S, Howard R, Desai A, Gourevitch D, Tolosa I, Vohra R. Psychological Prehabilitation Before Cancer Surgery: A Systematic Review. Ann Surg Oncol. 2015;22(13):4117–23. https://doi.org/10.1245/s10434-015-4550-z PMID: 15585997.

    Article  PubMed  Google Scholar 

  7. Carli F, Zavorsky GS. Optimizing functional exercise capacity in the elderly surgical population. Curr Opin Clin Nutr Metab Care. 2005;8(1):23–32. https://doi.org/10.1097/00075197-200501000-00005 Epub 2007 Jan 27. PMID: 17259638.

    Article  PubMed  Google Scholar 

  8. Harari D, Hopper A, Dhesi J, Babic-Illman G, Lockwood L, Martin F. Proactive care of older people undergoing surgery ('POPS’): designing embedding evaluating and funding a comprehensive geriatric assessment service for older elective surgical patients. Age Ageing. 2007;36(2):190–6. https://doi.org/10.1093/ageing/afl163 Epub ahead of print. PMID: 34227052.

    Article  PubMed  Google Scholar 

  9. Bolshinsky V, Li MH, Ismail H, Burbury K, Riedel B, Heriot A. Multimodal Prehabilitation Programs as a Bundle of Care in Gastrointestinal Cancer Surgery: A Systematic Review. Dis Colon Rectum. 2018;61(1):124–38. https://doi.org/10.1097/DCR.0000000000000987.

    Article  PubMed  Google Scholar 

  10. Katsura M, Kuriyama A, Takeshima T, Fukuhara S, Furukawa TA. Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and major abdominal surgery. Cochrane Database Syst Rev. 2015;10:CD010356. https://doi.org/10.1002/14651858.CD010356.pub2.

  11. Bruns ER, van den Heuvel B, Buskens CJ, van Duijvendijk P, Festen S, Wassenaar EB, van der Zaag ES, Bemelman WA, van Munster BC. The effects of physical prehabilitation in elderly patients undergoing colorectal surgery: a systematic review. Colorectal Dis. 2016;18(8):O267–77. https://doi.org/10.1111/codi.13429 PMID: 27332897.

    Article  CAS  PubMed  Google Scholar 

  12. Gillis C, Buhler K, Bresee L, Carli F, Gramlich L, Culos-Reed N, Sajobi TT, Fenton TR. Effects of Nutritional Prehabilitation With and Without Exercise on Outcomes of Patients Who Undergo Colorectal Surgery: A Systematic Review and Meta-analysis. Gastroenterology. 2018;155(2):391–410. https://doi.org/10.1053/j.gastro.2018.05.012 Epub 2018 May 8. PMID: 29750973.

    Article  PubMed  Google Scholar 

  13. Daniels SL, Lee MJ, George J, et al. Prehabilitation in elective abdominal cancer surgery in older patients: systematic review and meta-analysis. BJS Open. 2020;4(6):1022–41. https://doi.org/10.1002/bjs5.50347 Published online ahead of print, 2020 Sep 22.

    Article  PubMed Central  Google Scholar 

  14. Hughes MJ, Hackney RJ, Lamb PJ, Wigmore SJ, Christopher Deans DA, Skipworth RJE. Prehabilitation Before Major Abdominal Surgery: A Systematic Review and Meta-analysis. World J Surg. 2019;43(7):1661–8. https://doi.org/10.1007/s00268-019-04950-y PMID: 30788536.

    Article  Google Scholar 

  15. Berkel AEM, Bongers BC, Kotte H, et al. Effects of Community-based Exercise Prehabilitation for Patients Scheduled for Colorectal Surgery With High Risk for Postoperative Complications: Results of a Randomized Clinical Trial. Ann Surg. 2021. https://doi.org/10.1097/SLA.0000000000004702 Epub ahead of print. PMID: 33443905.

    Article  Google Scholar 

  16. Barberan-Garcia A, Ubre M, Pascual-Argente N, Risco R, Faner J, Balust J, Lacy AM, Puig-Junoy J, Roca J, Martinez-Palli G. Post-discharge impact and cost-consequence analysis of prehabilitation in high-risk patients undergoing major abdominal surgery: secondary results from a randomised controlled trial. Br J Anaesth. 2019;123(4):450–6. https://doi.org/10.1016/j.bja.2019.05.032 PMID: 28489682.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

Conflict of Interest

The authors did not receive support from any organization for the submitted work. The authors have no relevant financial or non-financial interests to disclose.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Surgical Care

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Patel, P.P., Luchette, F.A. Prehabilitation for High-Risk Surgical Patients. Curr Geri Rep 10, 182–186 (2021). https://doi.org/10.1007/s13670-021-00371-9

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13670-021-00371-9

Keywords

Navigation