Abstract
Traditionally, uncontained electromechanical morcellation was the preferred technique by gynecologists for tissue extraction in minimally invasive surgery. However, recent reports of inadvertent morcellation of undiagnosed sarcomas and dissemination of the tissue fragments have led to change in surgical approach. A number of techniques for contained morcellation have been proposed as an alternative to traditional techniques. A review of literature about contained tissue extraction in gynecological laparoscopic surgery has been performed in this article. Several techniques have been described, using either a specimen bag or a specially designed bag, performed by single-site or two-port technique. In-bag morcellation with specially designed bags offer an improvement over open morcellation and allows more patients to have the benefits of minimally invasive surgery without resorting to laparotomy.
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Garry R. Towards evidence-based laparoscopic entry techniques: clinical problems and dilemmas. Gynaecol Endosc. 1999;8:315–26.
Pelosi 3rd MA, Pelosi MA. The Pryor technique of uterine morcellation. Int J Gynaecol Obstet. 1997;58(3):299–303.
Steiner RA, Wight E, Tadir Y, Haller U. Electrical cutting device for laparoscopic removal of tissue from the abdominal cavity. Obstet Gynecol. 1993;81(3):471–4.
Hashizume M, Migo S, Tsugawa K, Tanoue K, Ohta M, Sugimachi K. Laparoscopic splenectomy with the newly devised morcellator. Hepato-Gastroenterology. 1998;45(20):554–7.
Bishoff JT. Laparoscopic radical nephrectomy: morcellate or leave intact? Definitely morcellate! Rev Urol. 2002;4(1):34–7.
Patient safety must be a priority in all aspects of care. Lancet Oncol. 2014;15(2):123.
US Food and Drug Administration. Quantitative assessment of the prevalence of unsuspected uterine sarcoma in women undergoing treatment of uterine fibroids. Issued April 17, 2014. http://www.fda.gov/downloads /MedicalDevices/Safety/AlertsandNotices /UCM393589.pdf. Accessed September 29, 2014.
US Food and Drug Administration. Updated Laparoscopic uterine power morcellation in hysterectomy and myomectomy: FDA safety communication. Issued November 24, 2014. http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices /ucm424443.htm. Accessed December 3, 2014. This warning statement from FDA changed the practice of laparoscopic power morcellation
Paul PG, Rengaraj V, Das T, Garg R, Thomas M, Khurd AS. Uterine sarcomas in patients undergoing surgery for presumed leiomyomas: 10 years’ experience. J Minim Invasive Gynecol. 2016;23(3):384–9.
Paul PG, Koshy AK. Multiple peritoneal parasitic myomas after laparoscopic myomectomy and morcellation. Fertil Steril. 2006;85(2):492–3 One of the first publication regarding parasitic myomas after laparoscopic morcellation.
Donnez O, Jadoul P, Squifflet J, Donnez J. A series of 3190 laparoscopic hysterectomies for benign disease from 1990 to 2006: evaluation of complications compared with vaginal and abdominal procedures. BJOG. 2009;116(4):492–500.
Cucinella G, Granese R, Calagna G, Somigliana E, Perino A. Parasitic myomas after laparoscopic surgery: an emerging complication in the use of morcellator? description of four cases. Fertil Steril. 2011;96(2):e90–6.
Leren V, Langebrekke A, Qvigstad E. Parasitic leiomyomas after laparoscopic surgery with morcellation. Acta Obstet Gynecol Scand. 2012;91(10):1233–6.
Nezhat C, Kho K. Iatrogenic myomas: new class of myomas? J Minim Invasive Gynecol. 2010;17(5):544–50.
Lieng M, Istre O, Busund B, Qvigstad E. Severe complications caused by retained tissue in laparoscopic supracervical hysterectomy. J Minim Invasive Gynecol. 2006;13(3):231–3.
Canis M, Pouly JL, Wattiez A, Mage G, Manhes H, Bruhat MA. Laparoscopic management of adnexal masses suspicious at ultrasound. Obstet Gynecol. 1997;89(5 Pt):679–83.
Abu-Rafeh B, Vilos GA, Misra M. Frequency and laparoscopic management of ovarian remnant syndrome. J Am Assoc Gynecol Laparosc. 2003;10(1):33–7.
Park JY, Park SK, Kim DY, Kim JH, Kim YM, Kim YT, et al. The impact of tumor morcellation during surgery on the prognosis of patients with apparently early uterine leiomyosarcoma. Gynecol Oncol. 2011;122(2):255–9.
Einstein MH, Barakat RR, Chi DS, Sonoda Y, Alektiar KM, Hensley ML, et al. Management of uterine malignancy found incidentally after supracervical hysterectomy or uterine morcellation for presumed benign disease. Int J Gynecol Cancer. 2008;18(5):1065–70.
Seidman MA, Oduyebo T, Muto MG, Crum CP, Nucci MR, Quade BJ. Peritoneal dissemination complicating morcellation of uterine mesenchymal neoplasms. PLoS One. 2012;7(11):e50058 .This study highlighted the unexpected diagnoses of leiomyoma variants or atypical and malignant smooth muscle tumors during morcellation
Anupama R, Ahmad SZ, Kuriakose S, Vijaykumar DK, Pavithran K, Seethalekshmy NV. Disseminated peritoneal leiomyosarcomas after laparoscopic “myomectomy” and morcellation. J Minim Invasive Gynecol. 2011;18(3):386–9.
Milad MP, Milad EA. Laparoscopic morcellator-related complications. J Minim Invasive Gynecol. 2014;21(3):486–91.
Rivard C, Salhadar A, Kenton K. New challenges in detecting, grading, and staging endometrial cancer after uterine morcellation. J Minim Invasive Gynecol. 2012;19(3):313–6.
Desai VB, Guo XM, Xu X. Alterations in surgical technique after FDA statement on power morcellation. Am J Obstet Gynecol. 2015;212:685–7.
Cohen SL, Einarsson JI, Wang KC, Brown D, Boruta D, Scheib SA, et al. Contained power morcellation within an insufflated isolation bag. Obstet Gynecol. 2014;124(3):491–7 First study of in-bag morcellation by single site and multiport technique.
Shibley KA. Feasibility of intra-abdominal tissue isolation and extraction, within an artificially created pneumoperitoneum, at laparoscopy for gynecologic procedures. J Minim Invasive Gynecol. 2012;19(6):S75 .First description of in-bag morcellation by single site technique in literature
Kujansuu S, Salari BW, Galloway M, Findley A, Yaklic JL, Massengill JC, et al. Contained morcellation using the GelPOINT advance access platforms and 3 M Steri-drape endobag. Fertil Steril. 2015;103(5):e36.
Aoki Y, Matsuura M, Matsuno T, Yamamoto T. Single-site in-bag morcellation achieved via direct puncture of the pneumoperitoneum cap, a cordless electric morcellator, and a 5-mm flexible scope. Eur J Obstet Gynecol Reprod Biol. 2016;201:126–30.
Advincula AP. Tissue extraction: can the pendulum change direction? J Fam Practice. 2016;28(6):8–12.
Einarsson JI, Cohen SL, Fuchs N, Wang KC. In-bag morcellation. J Minim Invasive Gynecol. 2014;21(5):951–3.
Kanade TT, McKenna JB, Choi S, Tsai BP, Rosen DM, Cario GM, et al. Sydney contained in bag morcellation for laparoscopic myomectomy. J Minim Invasive Gynecol. 2014;21(6):981.
McKenna JB, Kanade TT, Choi S, Tsai BP, Rosen DM, Cario GM. The Sydney contained in bag morcellation technique. J Minim Invasive Gynecol. 2014;21(6):981.
Cholkeri-Singh A, Miller CE. Power morcellation in a specimen bag. J Minim Invasive Gynecol. 2015;22(2):160.
Srouji SS, Kaser DJ, Gargiulo AR. Techniques for contained morcellation in gynecologic surgery. Fertil Steril. 2015;103(4):e34.
Springborg HH, Istre O. Complete plastic lining of the abdominal cavity during laparoscopic electromechanical morcellation —a promising technique. Gynecol Surg. 2015;12(2):133–7.
Akdemir A, Taylan E, Zeybek B, Ergenoglu AM, Sendag F. Innovative technique for enclosed morcellation using a surgical glove. Obstet Gynecol. 2015;125(5):1145–9.
Paul PG, Thomas M, Das T, Patil S, Garg R. Contained morcellation for laparoscopic myomectomy within a specially designed bag. J Minim Invasive Gynecol. 2016;23(2):257–60 This publication describes the use of a specially designed bag for two-port in-bag morcellation avoiding bag puncture.
Rimbach S, Holzknecht A, Nemes C, Offner F, Craina M. A new in-bag system to reduce the risk of tissue morcellation: development and experimental evaluation during laparoscopic hysterectomy. Arch Gynecol Obstet. 2015;292(6):1311–20.
Rimbach S, Holzknecht A, Schmedler C, Nemes C, Offner F. First clinical experiences using a new in-bag morcellation system during laparoscopic hysterectomy. Arch Gynecol Obstet. 2016;294(1):83–93.
Vargas MV, Cohen SL, Fuchs-Weizman N, Wang KC, Manoucheri E, Vitonis AF, et al. Open power morcellation versus contained power morcellation within an insufflated isolation bag: comparison of perioperative outcomes. J Minim Invasive Gynecol. 2015;22(3):433–8 One of the two comparative studies between open and contained power morcellation.
Winner B, Porter A, Velloze S, Biest S. Uncontained compared with contained power morcellation in total laparoscopic hysterectomy. Obstet Gynecol. 2015;126(4):834–8 One of the two comparative studies between open and contained power morcellation.
Cohen SL, Greenberg JA, Wang KC, Srouji SS, Gargiulo AR, Pozner CN, et al. Risk of leakage and tissue dissemination with various contained tissue extraction (CTE) techniques: an in vitro pilot study. J Minim Invasive Gynecol. 2014;21(5):935–9.
Cohen SL, Morris SN, Brown DN, Greenberg JA, Walsh BW, Gargiulo AR, et al. Contained tissue extraction using power morcellation: prospective evaluation of leakage parameters. Am J Obstet Gynecol. 2016;214(257):e1–6.
Miller CE, Steller C, Sasaki K, Cholkeri-Singh A. Review and outcomes of power morcellation using an innovative contained bag system. 2015;104(3):e175.
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P.G. Paul declares a patent pending titled “future modification of the MorSafe bag” and Dr. Paul declares to be the first user of the MorSafe bag. Aditya S. Khurd, Radhika K. T., Saumya Bulusu, and George Paul declare that they have no conflict of interest.
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In this article, the studies performed by the authors were formally approved by the ethics committee (Institutional Review Board) of Paul’s Hospital, Kochi, Kerala, India.
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This article is part of the Topical Collection on Minimally Invasive Gynecologic Surgery
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Paul, P.G., Khurd, A.S., Radhika K., T. et al. Techniques for Laparoscopic Contained Tissue Extraction. Curr Obstet Gynecol Rep 5, 325–332 (2016). https://doi.org/10.1007/s13669-016-0185-8
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DOI: https://doi.org/10.1007/s13669-016-0185-8