Abstract
Sweet potato is a rich source of antioxidant phytohemicals, like β-carotene, vitamin C, anthocyanins, xanthophylls, and phenolics, which are relevant for providing dietary protections against chronic oxidative stress-associated diseases, like type 2 diabetes. However, the health protective phytochemical profiles and associated antioxidant and anti-diabetic properties of sweet potatoes vary widely between different flesh color and among cultivars. Therefore, the aim of this study was to screen aqueous and ethanol (12%) extracts of seven sweet potato cultivars with different flesh colors (white–yellow, orange, and purple) for their phenolic phytochemical-linked functional qualities. Total soluble phenolic (TSP) content, phenolic profile, protein content, total antioxidant activity, anti-hyperglycemic function relevant α-amylase, α-glucosidase, and anti-hypertensive function related angiotensin-I-converting enzyme (ACE) inhibitory activities of sweet potato cultivars were determined using rapid in vitro assay models. The purple flesh cv. NIC-413 had significantly higher phenolic content (2.8 mg GAE 100 g−1 FW) and associated high antioxidant activity. Catechin, gallic, and dihydroxybenzoic acids were found in all cultivars, while chlorogenic acid was present only in purple-flesh cultivar. Anti-hyperglycemic property relevant α-amylase (74–84%), and α-glucosidase (21–60%) enzyme inhibitory activities were present in all sweet potato cultivars. Additionally, anti-hypertensive property relevant ACE (10–88%) enzyme inhibitory activity were present across all sweet potato cultivars. The results of this in vitro screening study suggested that sweet potato cultivars like NIC-413, Murasaki, Evangeline, and Covington are good dietary source of phenolic antioxidants and can be relevant for anti-hyperglycemic and anti-hypertensive benefits to target type 2 diabetes associated health risks.
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The data presented in this study are available on request from the corresponding author.
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Acknowledgements
This research work was supported by Indian Council of Agricultural Research (ICAR) under Netaji Subhas ICAR-International fellowship. We also want to thank Lonny and Sandy Dietz of Whitewater Gardens Farm (Altura, MN, USA) for providing 2 sweet potato cultivars for this study.
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Conceptualization, KS and DS; methodology, PC; DS, KP, MD, HHV and KS validation, PC. DS and KS; formal analysis, PC; DS and KS; investigation, PC; DS; and KP; resources, KS; data curation, PC and DS; writing—original draft preparation, PC and DS; writing—review and editing, KS, HHV and MD; visualization, KS; supervision, KS and DS; project administration, KS.
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Communicated by Jeong Hee Choi.
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Chintha, P., Sarkar, D., Pecota, K. et al. Phenolic bioactive-linked antioxidant, anti-hyperglycemic, and antihypertensive properties of sweet potato cultivars with different flesh color. Hortic. Environ. Biotechnol. 64, 877–893 (2023). https://doi.org/10.1007/s13580-023-00515-0
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DOI: https://doi.org/10.1007/s13580-023-00515-0