Abstract
Today, more advanced therapy and diagnosis can be achieved by recent progress in nanomedicine in the field of nuclear medicine. 161Tb is a promising NCA radionuclide due to its unique characteristics such as 6.9 days’ half-life and conversion and Auger electron emission beside the beta and gamma decays. Production of 161Tb through 160Gd (n,γ) 161Gd → 161Tb nuclear reaction was investigated by irradiation of two forms of natural and enriched Gd and GdNPs in Tehran Research Reactor. Gadolinium nanoparticles were characterized with FT-IR, TEM, and Energy dispersive X-ray (EDX) analysis. In this study, first, the radioactivity of 161Tb and other impurities that are produced during the production is calculated by MATLAB software. Then, the theoretical and experimental comparison of activity values of 161Tb and other impurities produced by irradiation of bulk and nanoscale Gd targets has been carried out. The results showed that the activity values obtained from irradiation of nanoparticles of gadolinium (size of ≤ 4 nm) are about 3 times more than bulk ones.
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Salek, N., Vosoughi, S., Roudsari, S.T. et al. Theoretical and Experimental Assessment of 161Tb Produced by Irradiation of Bulk and Nanoscale Gd Targets in TRR. Braz J Phys 53, 65 (2023). https://doi.org/10.1007/s13538-023-01283-z
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DOI: https://doi.org/10.1007/s13538-023-01283-z