Abstract
Arthropod-borne infections like malaria, dengue and chikungunya fever are transmitted by mosquitoes. The present report describes an unusual case of mixed infection with malaria, dengue and chikungunya viruses in a 21 year old male patient from New Delhi, India during monsoon season of 2016. The malarial fever was diagnosed by thin slide microscopy and antigen test. Chikungunya virus IgM was detected in the sample by the card test. Dengue and chikungunya viruses were further confirmed by RT-PCR for CprM and E1 gene respectively. Phylogenetic analysis clustered the study dengue virus serotype 3 sequence in the genotype III. Thus, the mono infections can not be differentiated from concurrent infections on the basis of clinical symptoms, the appropriate laboratory diagnosis is essential for the accurate pathogen confirmation. Precise and appropriate identification of the multiple pathogens in such clinical cases will assist in the effective management of these arthropod mediated infections.
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Acknowledgements
Ayesha Tazeen is supported by Research Fellowship of the University Grants Commission, Government of India. Malik Hisamuddin is supported by Senior Research Fellowship of Indian Council of Medical Research, New Delhi, India. Work in our laboratory is supported by Grants from University Grants Commission and Council of Scientific and Industrial Research, Government of India. We acknowledge the support of laboratory staff of Dr. M.A. Ansari Health Centre, Jamia Millia Islamia, New Delhi.
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Abdullah, M., Tazeen, A., Hisamuddin, M. et al. A clinical report on mixed infection of malaria, dengue and chikungunya from New Delhi, India. VirusDis. 28, 422–424 (2017). https://doi.org/10.1007/s13337-017-0404-6
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DOI: https://doi.org/10.1007/s13337-017-0404-6