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Radical surgery for gastric cancer in octogenarian patients

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Abstract

To valuate feasibility and results of radical surgery in octogenarian patients with gastric cancer. We collected data on 60 patients that underwent gastrectomy with an R0 resection at our Institution from 2010 to 2015. Patients were divided into two groups: octogenarian (OG) (n = 26), consisting of patients aged 80–89 years, and younger (YG) (n = 34), consisting of patients under 80 years of age. All patients were treated with total or subtotal gastrectomy with lymphadenectomy. A D2-lymphadenectomy was performed in 11 and 24 patients, a D1+ in 5 and 4, a D1 in 8 and 6, and a D0 in 2 and 0 cases in OG and YG respectively. The overall morbidity rate was 42.3% (11/26) in OG and 29.4% (10/34) in YG, while 90-days mortality was observed in four (15.4%) and one (2.9%) patients in OG and YG, respectively. The median hospital stay was 9 days (2–31) and 9.5 days (6–66) in OG and YG, respectively. Gastrectomy with radical resection and limited lymphadenectomy should be recommended for octogenarian patients with good performance status and low co-morbidity.

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References

  1. Siegel R, Naishadham D, Jemal A (2013) Cancer statistics, 2013. CA Cancer J Clin 63(1):11–30

    Article  PubMed  Google Scholar 

  2. Bray F, Jemal A, Grey N, Ferlay J, Forman D (2012) Global cancer transitions according to the Human Development Index (2008-2030): a population-based study. Lancet Oncol 13(8):790–801

    Article  PubMed  Google Scholar 

  3. Saif MW, Makrilia N, Zalonis A, Merikas M, Syrigos K (2010) Gastric cancer in the elderly: an overview. Eur J Surg Oncol 36(8):709–717

    Article  CAS  PubMed  Google Scholar 

  4. Pisanu A, Montisci A, Piu S, Uccheddu A (2007) Curative surgery for gastric cancer in the elderly: treatment decisions, surgical morbidity, mortality, prognosis and quality of life. Tumori 93:478–484

    PubMed  Google Scholar 

  5. Katai H, Sasako M, Sano T, Fukagawa T (2004) Gastric cancer surgery in the elderly without operative mortality. Surg Oncol 13(4):235–238

    Article  PubMed  Google Scholar 

  6. Takeshita H, Ichikawa D, Komatsu S et al (2013) Surgical outcomes of gastrectomy for elderly patients with gastric cancer. World J Surg 37(12):2891–2898

    Article  PubMed  Google Scholar 

  7. Sasada S, Ikeda Y, Saitsu H, Saku M (2008) Characteristics of gastric cancer in patients over 80-years-old. Hepatogastroenterology 55(86–87):1931–1934

    PubMed  Google Scholar 

  8. Hayashi T, Yoshikawa T, Aoyama T, Ogata T, Cho H, Tsuburaya A (2012) Severity of complications after gastrectomy in elderly patients with gastric cancer. World J Surg 36(9):2139–2145

    Article  PubMed  Google Scholar 

  9. Liang YX, Deng JY, Guo HH et al (2013) Characteristics and prognosis of gastric cancer in patients aged ≥70 years. World J Gastroenterol 19(39):6568–6578

    Article  PubMed  PubMed Central  Google Scholar 

  10. Japanese Gastric Cancer Association (2011) Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer 14:101–112

  11. Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213

    Article  PubMed  PubMed Central  Google Scholar 

  12. Coluccia C, Ricci EB, Marzola GG, Molaschi M, Nano MG (1987) Gastric cancer in the elderly: results of surgical treatment. Int Surg 72(1):4–10

    CAS  PubMed  Google Scholar 

  13. Winslet MC, Mohsen YM, Powell J, Allum WH, Fielding JW et al (1996) The influence of age on the surgical management of carcinoma of the stomach. Eur J Surg Oncol 22(3):220–224

    Article  CAS  PubMed  Google Scholar 

  14. Damhuis RA, Tilanus HW (1995) The influence of age on resection rates and postoperative mortality in 2773 patients with gastric cancer. Eur J Cancer 31A(6):928–931

    Article  CAS  PubMed  Google Scholar 

  15. Roviello F, Marrelli D, De Stefano A, Messano A, Pinto E, Carli A (1998) Complications after surgery for gastric cancer in patients aged 80 years and over. Jpn J Clin Oncol 28(2):116–122

    Article  CAS  PubMed  Google Scholar 

  16. Kitamura K, Sugimachi K, Saku M (1999) Evaluation of surgical treatment for patients with gastric cancer who are over 80 years of age. Hepatogastroenterology 46(27):2074–2080

    CAS  PubMed  Google Scholar 

  17. Katai H, Sasako M, Sano T, Maruyama K (1998) The outcome of surgical treatment for gastric carcinoma in the elderly. Jpn J Clin Oncol 28(2):112–115

    Article  CAS  PubMed  Google Scholar 

  18. Eguchi T, Fujii M, Takayama T (2003) Mortality for gastric cancer in elderly patients. J Surg Oncol 84(3):132–136

    Article  PubMed  Google Scholar 

  19. Gretschel S, Estevez-Schwarz L, Hunerbein M, Schneider U, Schlag PM (2006) Gastric cancer surgery in elderly patients. World J Surg 30:1468–1474

    Article  PubMed  Google Scholar 

  20. Kumagai K, Hiki N, Nunobe S, Jiang X, Kubota T, Aikou S et al (2014) Potentially fatal complications for elderly patients after laparoscopy-assisted distal gastrectomy. Gastric Cancer 17:548–555

    Article  PubMed  Google Scholar 

  21. Endo S, Yoshikawa Y, Hatanaka N et al (2011) Treatment for gastric carcinoma in the oldest old patients. Gastric Cancer 14:139–143

    Article  PubMed  Google Scholar 

  22. United Nations (2009) World population ageing. http://www.un.org/esa/population/publications/WPA2009/WPA2009_WorkingPaper.pdf. Accessed Jul 2014

  23. Sakurai K, Muguruma K, Nagahara H et al (2015) The outcome of surgical treatment for elderly patients with gastric carcinoma. J Surg Oncol 111(7):848–854

    Article  PubMed  PubMed Central  Google Scholar 

  24. Mikami J, Kurokawa Y, Miyazaki Y et al (2015) Postoperative gastrectomy outcomes in octogenarians with gastric cancer. Surg Today 45(9):1134–1138

    Article  PubMed  Google Scholar 

  25. Takeuchi D, Koide N, Suzuki A et al (2015) Postoperative complications in elderly patients with gastric cancer. J Surg Res 198(2):317–326

    Article  PubMed  Google Scholar 

  26. Tran TB, Worhunsky DJ, Squires MH et al (2015) Outcomes of gastric cancer resection in octogenarians: a multi-institutional study of the U.S. gastric cancer collaborative. Ann Surg Oncol 22:4371–4379

    Article  PubMed  Google Scholar 

  27. Nakanoko T, Kakeji Y, Ando K et al (2015) Assessment of surgical treatment and postoperative nutrition in gastric cancer patients older than 80 years. Anticancer Res 35(1):511–515

    PubMed  Google Scholar 

  28. Kim JH, Chin HM, Jun KH (2015) Surgical outcomes and survival after gastrectomy in octogenarians with gastric cancer. J Surg Res 198(1):80–86

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. General Surgery Program, M.G. Vannini Hospital, Via di Acqua Bullicante 4, 00177, Rome, Italy

    Francesco Casella, Andrea Sansonetti & Roberto Verzaro

  2. Department of Surgery, S. Maria del Carmine Hospital, Corso Verona 24, 38068, Rovereto (Trento), Italy

    Andrea Zanoni

  3. Department of Life, Health and Environmental Sciences, General Surgery Program, M.G. Vannini Hospital, Piazzale Salvatore Tommasi 1, 67100, L’Aquila, Italy

    Cofini Vincenza & Alberto Capodacqua

Authors
  1. Francesco Casella
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  2. Andrea Sansonetti
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  3. Andrea Zanoni
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  4. Cofini Vincenza
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  5. Alberto Capodacqua
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  6. Roberto Verzaro
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Contributions

Study concept: FC, AS. Study design: FC, RV. Data acquisition: FC, AS. Quality control of data: AZ, RV. Data analysis and interpretation: FC, VC. Statistical analysis: AC, VC. Manuscript preparation: FC, AS. Manuscript editing: FC, RV. Manuscript review: AZ, RV. All authors have read and approved the final version.

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Correspondence to Francesco Casella.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Casella, F., Sansonetti, A., Zanoni, A. et al. Radical surgery for gastric cancer in octogenarian patients. Updates Surg 69, 389–395 (2017). https://doi.org/10.1007/s13304-017-0463-7

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  • DOI: https://doi.org/10.1007/s13304-017-0463-7

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