Skip to main content

Advertisement

Log in

Advancement flap in the management of chronic anal fissure: a prospective study

  • Original Article
  • Published:
Updates in Surgery Aims and scope Submit manuscript

Abstract

Lateral internal sphincterotomy is the surgical treatment of choice of chronic anal fissure after failure of conservative measures. Several randomized trials identified an overall risk of incontinence of 10 % mostly for flatus. Fissurectomy is the most commonly used procedure to preserve the integrity of the anal sphincters. However, a possible complication is keyhole defect that may lead to faecal soiling. In this study, chronic anal fissure (CAF) was treated by fissurectomy and anal advancement flap to preserve the anatomo-functional integrity of sphincters and to reduce healing time and the risk of anal stenosis. In patients with hypertonia, surgical treatment was combined with chemical sphincterotomy by injection of botulinum toxin to enhance tissue perfusion. Forty eight patients with CAF underwent fissurectomy and anal advancement flap. In 22 subjects with hypertonia of the internal anal sphincter, intrasphincter injection of 30 UI of botulinum toxin at the completion of the surgical operation was used. All patients were followed up to 24 months. Since the first defecation, the intensity and duration of pain were significantly reduced. Two patients had urinary retention, five had infections and three had partial breakdowns. No anal stenosis, keyhole deformity or necrosis flap was recorded. At the 24 months follow-up visit, anal incontinence was similar to those detected preoperatively. Only four recurrences were detected at 18 and 20 months. After medical treatment failure, fissurectomy with advancement flap is a valid sphincter-conserving procedure for treatment of anterior or posterior CAF, regardless of hypertonia of the internal anal sphincter.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Lindsey I, Jones OM, Cunningham C, Mortensen NJ (2004) Chronic anal fissure. Br J Surg 91:270–279

    Article  PubMed  CAS  Google Scholar 

  2. Collins EE, Lund JN (2007) A review of chronic anal fissure management. Tech Coloproctol 11:209–223

    Article  PubMed  CAS  Google Scholar 

  3. Nelson R (2005) Operative procedure for fissure in ano. Cochrane Database Syst Rev 2:CD002199

  4. Sileri P, Stolfi VM, Franceschilli L, Grande M, Di Giorgio A, D’Ugo S, Attinà G, D’Eletto M, Gaspari AL (2010) Conservative and surgical treatment of chronic anal fissure: prospective longer term results. J Gastrointest Surg 14:773–780

    Article  PubMed  Google Scholar 

  5. Patti R, Famà F, Barrera T, Migliore G, Di Vita G (2010) Fissurectomy and anal advancement flap for anterior chronic anal fissure without hypertonia of the internal anal sphincter in females. Colorectal Dis 12:1127–1130

    Article  PubMed  CAS  Google Scholar 

  6. Patti R, Famà F, Tornambè A, Restivo M, Di Vita G (2010) Early results of fissurectomy and advancement flap for resistant chronic anal fissure without hypertonia of the internal anal sphincter. Am Surg 76:206–210

    PubMed  Google Scholar 

  7. Patti R, Famà F, Tornambè, Asaro G, Di Vita G (2010) Fissurectomy combined with anal advancement flap and injection of botulinum toxin in treatment of anterior chronic anal fissure with hypertonia of internal anal sphincter: a pilot study. Tech Coloproctol 14:31–36

  8. Jones OM, Ramalingam T, Lindsey I, Cunningham C, George BD, Mortensen NJ (2005) Digital rectal examination of sphincter pressures in chronic anal fissure is unreliable. Dis Colon Rectum 48:349–352

    Article  PubMed  Google Scholar 

  9. Brisinda G, Cadeddu F, Brandara F, Maringa G, Vanella S, Nigro C, Maria G (2008) Botulinum toxin for recurrent anal fissure following lateral internal sphincterotomy. Br J Surg 95:774–778

    Article  PubMed  CAS  Google Scholar 

  10. Huskisson EC (1982) Measurement of pain. J Rheumatol 9:768–769

    PubMed  CAS  Google Scholar 

  11. Pescatori M, Anastasio G, Bottini C, Mentasti A (1992) New grading and scoring for anal incontinence. Evaluation of 335 patients. Dis Colon Rectum 35:482–487

    Article  PubMed  CAS  Google Scholar 

  12. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA (1999) Functional bowel disorders and functional abdominal pain. Gut 45:II 43–II 47

    Google Scholar 

  13. Giordano P, Gravante G, Grondona P, Ruggiero B, Porret T, Lunnis PJ (2009) Simple cutaneous anal advancement flap for resistant chronic anal fissure: a prospective study. World J Surg 33:1058–1063

    Article  PubMed  Google Scholar 

  14. Chambers W, Sajal R, Dixon A (2010) V–Y advancement flap as first-line treatment for all chronic anal fissures. Int J Colorectal Dis 25:645–648

    Article  PubMed  Google Scholar 

  15. Patel SD, Oxenam T, Praveen BV (2011) Medium term results of anal advancement flap compared with lateral sphincterotomy for the treatment of anal fissure. Int J Colorectal Dis. doi:10.1007/S00384-011-1234-4

  16. Ayantunde AA, Debrah SA (2006) Current concepts in anal fissures. World J Surg 30:2246–2260

    Article  PubMed  Google Scholar 

  17. Cho DY (2005) Controlled lateral sphincterotomy for chronic anal fissure. Dis Colon Rectum 48:1037–1041

    Article  PubMed  Google Scholar 

  18. Mentes BB, Ege B, Leventoglu S, Oguz M, Karadag A (2005) Extent of lateral internal sphincterotomy: up to the dentate line or up to the fissure apex? Dis Colon Rectum 48:365–370

    Article  PubMed  Google Scholar 

  19. Aigner F, Conrad F (2008) Fissurectomy for treatment of chronic anal fissures. Dis Colon Rectum 51:1163

    Article  PubMed  Google Scholar 

  20. Meier zu Eissen J (2001) Chronic anal fissure, therapy. Kongressbd Dtsch Ges Chir Kongr 118:654–656

    Google Scholar 

  21. Mousavi SR, Sharifi M, Mehdikhah Z (2009) A comparison between the results of fissurectomy and lateral internal sphincterotomy in the surgical management of chronic anal fissure. J Gastrointest Surg 13:1279–1282

    Article  PubMed  CAS  Google Scholar 

  22. Engel AF, Eijsbouts QA, Balk AG (2002) Fissurectomy and isosorbide dinitrate for chronic fissure in ano not responding to conservative treatment. Br J Surg 89:79–83

    Article  PubMed  CAS  Google Scholar 

  23. Lindsey I, Cunningham C, Jones OM, Francis C, Mortensen NJ (2004) Fissurectomy–botulinum toxin: a novel sphincter-sparing procedure for medically resistant chronic anal fissure. Dis Colon Rectum 47:1947–1952

    Article  PubMed  Google Scholar 

  24. Baraza W, Boereboom C, Shorthouse A, Brown S (2008) The long-term efficacy of fissurectomy and botulinum toxin injection for chronic anal fissure in females. Dis Colon Rectum 51:239–243

    Article  PubMed  Google Scholar 

  25. Scholz T, Hetzer FH, Dindo D, Demartines N, Clavien PA, Hahlaser D (2007) Long-term follow-up after combined fissurectomy and Botox injection for chronic anal fissures. Int J Colorectal Dis 22:1077–1081

    Article  PubMed  Google Scholar 

  26. Arthur JD, Makin CA, El-Sayed TY, Walsh CJ (2008) A pilot comparative study of fissurectomy/diltiazem and fissurectomy/botulinum toxin in the treatment of chronic anal fissure. Tech Coloproctol 12:331–336

    Article  PubMed  CAS  Google Scholar 

  27. Aivaz O, Rayhanabad J, Nguyen V, Haigh PI, Abbas M (2009) Botulinum toxin A with fissurectomy is a viable alternative to lateral internal sphincterotomy for chronic anal fissure. Am Surg 75:925–928

    PubMed  Google Scholar 

  28. Witte ME, Klaase JM, Koop R (2010) Fissurectomy combined with botulinum toxin A injection for medically resistant chronic anal fissures. Colorectal Dis 12:163–169

    Article  Google Scholar 

  29. Ouaïssi M, Giger U, Sielezneff I, Yawovi KA, Pamela A, Pirro N, Sastre B (2011) Mucosal advancement flap anoplasty for chronic anal fissure resistant to conservative therapy. World J Surg 35:900–904

    Article  PubMed  Google Scholar 

  30. Pigot F, Juguet F, Bouchard D, Castinel A, Vove JP (2011) Prospective survey of secondary bleeding following anorectal surgery in a consecutive series of 1,269 patients. Clin Res Hepathol Gastroenterol 35:41–47

    Article  CAS  Google Scholar 

  31. Nyam DC, Wilson RG, Stewart KJ et al (1995) Island advancement flaps in the management of anal fissures. Br J Surg 82:326–328

    Article  PubMed  CAS  Google Scholar 

  32. Pescatori M, Ayabaca SM, Cafaro D (2002) Tailored sphincterotomy or fissurectomy and anoplasty? Dis Colon Rectum 45:1563–1564

    Article  PubMed  Google Scholar 

  33. Kenefick NJ, Gee AS, Durdey P (2002) Treatment of resistant anal fissure with advancement anoplasty. Colorectal Dis 4:463–466

    Article  PubMed  CAS  Google Scholar 

  34. Singh M, Sharma A, Gardiner A, Duthie GS (2005) Early results of a rotational flap to treat chronic anal fissures. Int J Colorectal Dis 20:339–342

    Article  PubMed  Google Scholar 

  35. Samson RB, Stewart WR (1970) Sliding skin grafts in the treatment of anal fissures. Dis Colon Rectum 13:372–375

    Article  PubMed  CAS  Google Scholar 

  36. Hancke E, Rikas E, Suchan K, Volke K (2010) Dermal flap coverage for chronic anal fissure: lower incidence of anal incontinence compared to lateral internal sphincterotomy after long-term follow-up. Dis Colon Rectum 53:1563–1568

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gaetano Di Vita.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Patti, R., Guercio, G., Territo, V. et al. Advancement flap in the management of chronic anal fissure: a prospective study. Updates Surg 64, 101–106 (2012). https://doi.org/10.1007/s13304-012-0147-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13304-012-0147-2

Keywords

Navigation