Skip to main content

Advertisement

SpringerLink
Log in

Laparoscopic versus open distal pancreatectomy in pancreatic tumours: a case–control study

  • Original Article
  • Published:
Updates in Surgery Aims and scope Submit manuscript

Abstract

Laparoscopic distal pancreatectomy has become an increasingly used procedure in the surgical treatment of benign or borderline cystic and endocrine tumours. The feasibility and safety of this technique is well known but its results when compared with open distal pancreatectomy were rarely reported in literature. Data from 22 consecutive patients who underwent laparoscopic distal pancreatectomy were recorded in a prospective database from January 2006 to January 2010. These patients were matched with 22 patients who underwent open distal pancreatectomy from January 2000 to December 2005, regarding age, gender, American Society of Anesthesiologists score, pancreatic pathology. Intraoperative parameters and postoperative outcome were compared between the two groups. Blood loss, amount of analgesic drugs administered, postoperative mortality and morbidity and pancreatic fistula rate were similar in laparoscopic and open groups. Tumour size was significantly smaller in laparoscopic group (2.0 ± 3.3 vs. 5.0 ± 4.2 cm; P = 0.038). Operative time was significantly shorter in open group (145 ± 49 vs. 225 ± 83 min, P = 0.045). Time to adequate oral intake and length of postoperative hospital stay were significantly better in laparoscopic group than in open group (3.0 ± 0.8 vs. 4.0 ± 0.7 days; P = 0.030 and 8.0 ± 1.3 vs. 11.0 ± 3.0 days; P = 0.011, respectively). Laparoscopic distal pancreatectomy is a feasible and safe surgical approach as well as open distal pancreatectomy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Lebedyev A, Zmora O, Kuriansky J, Rosin D, Khaikin M, Shabtai M, Ayalon A (2004) Laparoscopic distal pancreatectomy. Surg Endosc 18:1427–1430

    Article  CAS  PubMed  Google Scholar 

  2. Matsumoto T, Hirano S, Yada K, Himeno Y, Shibata K, Aramaki M, Kawano K, Kitano S (2005) Safety and efficacy of laparoscopic distal pancreatectomy for the treatment of pancreatic disease. J Hepatobiliary Pancreat Surg 12:65–70

    Article  PubMed  Google Scholar 

  3. Assalia A, Gagner M (2004) Laparoscopic pancreatic surgery for islet cell tumors of the pancreas. World J Surg 28:1239–1247

    Article  PubMed  Google Scholar 

  4. Fernandez Cruz L, Martinez I, Gilbert R, Cesar-Borges G, Astudillo E, Navarro S (2004) Laparoscopic distal pancreatectomy combined with preservation of the spleen for cystic neoplasm of the pancreas. J Gastrointest Surg 8:493–501

    Article  PubMed  Google Scholar 

  5. Edwin B, Mala T, Mathisen O, Gladhaug I, Buanes T, Lunde OC, Soreide O, Bergan A, Fosse E (2004) Laparoscopic resection of the pancreas: a feasibility study of the short term outcomes. Surg Endosc 18:407–411

    Article  CAS  PubMed  Google Scholar 

  6. Shimizu S, Tanaka M, Konomi H, Mizumoto K, Yamaguchi K (2004) Laparoscopic pancreatic surgery: current indications and surgical results. Surg Endosc 18:402–408

    Article  CAS  PubMed  Google Scholar 

  7. Tagaya N, Kasama K, Suzuki N, Taketsuka S, Horie K, Furihata M, Kubota K (2003) Laparoscopic resection of the pancreas and review of the literature. Surg Endosc 17:201–206

    Article  CAS  PubMed  Google Scholar 

  8. Fernandez Cruz L, Saenz A, Astudillo E, Martinez I, Hoyos S, Pantoja JP, Navarro S (2002) Outcomes of laparoscopic pancreatic surgery: endocrine and non endocrine tumors. World J Surg 26:1057–1065

    Article  CAS  PubMed  Google Scholar 

  9. Patterson EJ, Gagner M, Salky B, Inabnet WB, Brower S, Edye M, Gurland B, Reiner M, Pertsemlides D (2001) Laparoscopic pancreatic resections: single-institution experience of 19 patients. J Am Coll Surg 193:281–287

    Article  CAS  PubMed  Google Scholar 

  10. Velanovich V (2006) The lasso technique for laparoscopic distal pancreatectomy. Surg Endosc 20:1766–1771

    Article  CAS  PubMed  Google Scholar 

  11. Velanovich V (2006) Case-control comparison of laparoscopic versus open distal pancreatectomy. J Gastrointestinal Surg 10:95–98

    Article  Google Scholar 

  12. Casadei R, Zanini N, Morselli-Labate M et al (2006) Prognostic factors in periampullary and pancreatic tumor resection in the elderly patients. World J Surg 30:1992–2001

    Article  CAS  PubMed  Google Scholar 

  13. Bassi C, Dervenis C, Butturini G et al (2005) Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 138:8–13

    Article  PubMed  Google Scholar 

  14. Soper NJ, Brunt LM, Dunnegan DL, Meininger TA (1994) Laparoscopic distal pancreatectomy in the porcine model. Surg Endosc 8:57–60

    Article  CAS  PubMed  Google Scholar 

  15. Sussman LA, Christie R, Whittle DE (1996) Laparoscopic excision of distal pancreas including insulinoma. ANZ J Surg 66:414–416

    Article  CAS  Google Scholar 

  16. Mabrut JY, Fernandez Cruz L, Azagra JS, Bassi C, Delvaux G, Weerts J, Fabre JM, Boulez J, Baulieux J, Peix JL, Gigot JF (2005) Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients. Surgery 137:597–605

    Article  PubMed  Google Scholar 

  17. Melotti G, Butturini G, Piccoli M, Casetti L, Bassi C, Mullineris B, Lazzaretti MG, Pederzoli P (2007) Laparoscopic distal pancreatectomy. Results on a consecutive series of 58 patients. Ann Surg 246:77–82

    Article  PubMed  Google Scholar 

  18. Briggs CD, Mann CD, Irving GRB, Neal CP, Peterson M, Cameron IC, Berry DP (2009) Systematic review of minimally invasive pancreatic resection. J Gastrointest Surg 13:1129–1137

    Article  PubMed  Google Scholar 

  19. Cunha AS, Beau C, Rault A, Catargi B, Collet D, Masson B (2006) Laparoscopic versus open approach for solitary insulinoma. Surg Endosc 21:103–108

    Article  Google Scholar 

  20. Eom BW, Jang JY, Lee E, Han HS, Yoon YS, Kim SW (2008) Clinical outcomes compared between laparoscopic and open distal pancreatectomy. Surg Endosc 22:1334–1338

    Article  CAS  PubMed  Google Scholar 

  21. Matsumoto T, Shibata K, Ohta M, Iwaki K, Uchida H, Yada K, Mori M, Kitano S (2008) Laparoscopic distal pancreatectomy and open distal pancreatectomy: a nonrandomized comparative study. Surg Laparosc Endosc Percutan Tech 18:340–343

    Article  PubMed  Google Scholar 

  22. Kim SC, Park KT, Hwang JW, Shin HC, Lee SS, Seo DW, Lee SK, Kim MH, Han DJ (2008) Comparative analysis of clinical outcomes for laparoscopic distal pancreatic resection and open distal pancreatic resection at a single institution. Surg Endosc 22:2261–2268

    Article  PubMed  Google Scholar 

  23. Baker MS, Bentrem DJ, Ujiki MB, Stocker S, Talamonti MS (2009) A prospective single institution comparison of peri-operative outcomes for laparoscopic and open distal pancreatectomy. Surgery 146:635–645

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

  1. Dipartimento di Scienze Chirurgiche e Anestesiologiche, Chirurgia Generale-Minni, Alma Mater Studiorum, Università di Bologna, Policlinico S. Orsola-Malpighi, Via Massarenti, 9, 40138, Bologna, Italy

    Riccardo Casadei, Claudio Ricci, Marielda D’Ambra, Nicola Marrano, Vincento Alagna, Daniela Rega, Francesco Monari & Francesco Minni

Authors
  1. Riccardo Casadei
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Claudio Ricci
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marielda D’Ambra
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nicola Marrano
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Vincento Alagna
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Daniela Rega
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Francesco Monari
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Francesco Minni
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Riccardo Casadei.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Casadei, R., Ricci, C., D’Ambra, M. et al. Laparoscopic versus open distal pancreatectomy in pancreatic tumours: a case–control study. Updates Surg 62, 171–174 (2010). https://doi.org/10.1007/s13304-010-0027-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13304-010-0027-6

Keywords

Search

Navigation