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Advanced Polymer-Based Bioink Technology for Printing Soft Biomaterials

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Abstract

Remarkable advancement in 3D printing technology in recent years has already transformed many aspects of industrial manufacturing. The immense potential of 3D printing is already being explored in state-of-the-art biomedical research field. Often termed “bioprinting”, 3D printing is utilized to generate biological structures with high resolution and specificity for tissue engineering and regenerative medical applications. With the maturation of bioprinting apparatus, now the focus is shifting to engineering “bioinks” that can accommodate the versatility of biological systems, while still maintaining their printability. In this review, bioink technologies based on various polymers to produce soft biomaterials, such as hydrogels and elastomers, having a diverse array of physicochemical and bioactive properties are introduced and highlighted.

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Authors and Affiliations

  1. Department of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Korea

    Kangseok Lee & Chaenyung Cha

  2. School of Materials Science and Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Korea

    Kangseok Lee & Chaenyung Cha

  3. Center for Multidimensional Programmable Matter, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Korea

    Kangseok Lee & Chaenyung Cha

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  1. Kangseok Lee
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The main focus of bioink technology going forward would be finding the right formulations for successfully managing printability, biomaterials properties, and biocompatibility.

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Footnote: The image from this article is used as the cover image of the Volume 28, Issue 8.

Acknowledgments: This study was supported by the 2020 Research Fund (1.200039.01) of UNIST (Ulsan National Institute of Science and Technology), and Basic Science Research Program and Bio & Medical Technology Development Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (2018R1D1A1B07048522, 2017M3A9C6033875).

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Lee, K., Cha, C. Advanced Polymer-Based Bioink Technology for Printing Soft Biomaterials. Macromol. Res. 28, 689–702 (2020). https://doi.org/10.1007/s13233-020-8134-9

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