References
Isoardi KZ, Henry C, Harris K, Isbister GK. Activated charcoal and bicarbonate for aspirin toxicity: a retrospective series. J Med Toxicol. 2022;18(1):30–37.
Howland MA. Pharmacokinetic and Toxicokinetic Principles. In: Nelson LS, Howland MA, Lewin NA, Smith SW, Goldfrank LR, Hoffman RS, editors. Goldfrank's Toxicologic Emergencies, 11th edition. New York: McGraw-Hill Education; 2019. p. 140–154.
Levy G. Clinical pharmacokinetics of salicylates: a re-assessment. Brit J Clin Pharmaco. 1980;10:285S-290S.
Levy G. Pharmacokinetics of salicylate elimination in man. J Pharm Sci. 1965;54:959–67.
Shively RM, Hoffman RS, Manini AF. Acute salicylate poisoning: risk factors for severe outcome. Clin Toxicol. 2017;55:1–6.
Morgan AG, Polak A. The excretion of salicylate in salicylate poisoning. Clin Sci. 1971;41:475–84.
Levy G, Tsuchiya T. Effect of activated charcoal on aspirin absorption in man Part I. Clin Pharmacol Ther. 1972;13:317–22.
Hill JB. Salicylate intoxication. New Engl J Medicine. 1973;288:1110–3.
Prescott LF, Balali-Mood M, Critchley JA, Johnstone AF, Proudfoot AT. Diuresis or urinary alkalinisation for salicylate poisoning? Br Medical J Clin Res Ed. 1982;285:1383.
Barone JA, Raia JJ, Huang YC. Evaluation of the effects of multiple-dose activated charcoal on the absorption of orally administered salicylate in a simulated toxic ingestion model. Ann Emerg Med. 1988;17:34–7.
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Bloom, J., Howland, M.A. & Cohen, E.T. Reflections on Aspirin Toxicity: Interpreting Effects of Sodium Bicarbonate and Activated Charcoal. J. Med. Toxicol. 18, 172–173 (2022). https://doi.org/10.1007/s13181-022-00883-6
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DOI: https://doi.org/10.1007/s13181-022-00883-6